Results 171 to 180 of about 85,922 (319)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Exact sequence interpolation with transformers. [PDF]

Math Found Mach Learn
Alcalde A, Fantuzzi G, Zuazua E.
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Fine-Tuning and Benchmarking Transformer Models for Multiclass Classification of Clinical Research Papers: Retrospective Modeling Study. [PDF]

JMIR AI
Zhou F, Lokker C, Parrish R, Haynes RB, Iorio A, Saha A, Afzal M.   +6 more
europepmc   +1 more source

Study of surface discharge behaviour at the oil-pressboard interface

, 2013
This thesis is concerned with the surface discharge behaviour at the oil-pressboard interface. For large transformers this is classified as a serious failure mode because it can lead to catastrophic failure under normal AC voltage operating conditions ...
Zainuddin, H
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

A systematic comparison of transformers and ConvNets for root segmentation across nine datasets. [PDF]

Plant Methods
Smith AG, Lamprinidis S, Seethepalli A, York LM, Han E, Möhl P, Boulata K, Thorup-Kristensen K, Petersen J.   +8 more
europepmc   +1 more source

Lightweight transformers for clinical natural language processing

Specialised pre-trained language models are becoming more frequent in Natural language Processing (NLP) since they can potentially outperform models trained on generic texts. BioBERT (Sanh et al., Distilbert, a distilled version of bert: smaller, faster,
Abel, L, Rohanian, O, Clifton, DA, Kouchaki, S, Clifton, L, Abe, R, Absil, L, Abbas, A, Abdukahil, SA, Nouriborji, M, Abdulkadir, NN, Abrous, A, Jauncey, H, Nooralahzadeh, F, Merson, L, et al.   +15 more
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Applying transformer-based deep learning models in image-driven cancer diagnosis: a comprehensive bibliometric analysis of global research trends. [PDF]

Front Oncol
Gong L, Wen T, Zeng X, Liu X, Li M, Sun J, Zheng J.   +6 more
europepmc   +1 more source