Results 191 to 200 of about 1,224 (273)

Novel Biological Approach to Mitigate Methane Emissions from Livestock Slurry through Microbial Conversion of Glycerol. [PDF]

open access: yesEnviron Sci Technol
Ambrose HW   +6 more
europepmc   +1 more source

Gold Single‐Atom Catalysts Enable Selective Shuttle Hydrochlorination of Alkynes

open access: yesAngewandte Chemie International Edition, EarlyView.
Gold single‐atom catalysts on activated carbon enable heterogeneous shuttle hydrochlorination of terminal alkynes to vinyl chlorides with high chemo‐ and stereo‐selectivity thanks to cooperation between Au(I) sites and the support. The catalytic system combines broad substrate compatibility, simplified separation, and recoverability, paving the way for
Marc‐Eduard Usteri   +8 more
wiley   +1 more source

Synthesis of a Stable Hydrophilic trans‐Cyclooctene Amino Acid Unlocks Fast Bioorthogonal Click Chemistry for the Generation of Antibody‐Drug Conjugates by Genetic Code Expansion

open access: yesAngewandte Chemie International Edition, EarlyView.
A novel trans‐cyclooctene (TCO) based noncanonical amino acid (ncAA) is reported, characterized by high hydrophilicity and remarkable stability to trans‐cis isomerization. Its incorporation via genetic code expansion into an antibody and subsequent conjugation resulted in a highly efficacious antibody‐drug conjugate (ADC).
Georgi R. Genov   +4 more
wiley   +1 more source

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