Results 101 to 110 of about 52,484 (215)

Directed donations for unvaccinated blood: A departure from evidence‐based medicine associated with clinical harm, resource waste, and oversight gaps in a two‐year single‐center series

Transfusion, EarlyView.
Abstract Background and Objectives Requests for “unvaccinated” blood have been discouraged by professional and regulatory bodies because they lack scientific support and may negatively impact patient care. We describe a single‐center series in which patients or surrogates refused standard blood components unless sourced from directed donors perceived ...
Jeremy W. Jacobs, Erika Hall, Toufik Tahiri, Princess Taylor, Chaitali Patel, Miriam Brown, Kaycie Atchison, Angela Mueller, Deva Sharma, Garrett S. Booth   +9 more
wiley   +1 more source

Ferroptosis-associated changes in transfusion-related acute lung injury in Sprague Dawley rats

Open Medicine
Transfusion-related acute lung injury (TRALI) is a severe transfusion complication, and oxidative stress has been implicated in its pathophysiology. Whether ferroptosis-associated changes are present in TRALI remains unclear.
Cai Chunli, Cai Chunqian, Lei Yaorong, Chen Huayu, Xu Qiao, He Jing   +5 more
doaj   +1 more source

Transfusion‐related alpha‐gal syndrome: Two new cases expanding the demographic and geographic spectrum, and evidence of a diagnostic gap in allergic transfusion reaction evaluation

Transfusion, EarlyView.
Abstract Background Transfusion‐related alpha‐gal syndrome (TRAGS) has recently been proposed as a cause of allergic transfusion reactions (ATRs) in which alpha‐gal‐specific IgE in sensitized group O (or potentially group A) recipients reacts with epitopes on group B or AB plasma‐containing components.
Mackenzie Foster, Miriam Brown, Angela Mueller, Toufik Tahiri, Kaycie Atchison, Deva Sharma, Cosby A. Stone Jr., Jonathan Tucci, Garrett S. Booth, Jeremy W. Jacobs   +9 more
wiley   +1 more source

Mother Who Experienced TRALI After a Caesarian Section on the Indication of Severe Pre-eclampsia with a Macrosomic Fetus

Andalas Obstetrics and Gynecology Journal
Introduction: Transfusion-Related Acute Lung Injury (TRALI) is a severe, often fatal, complication of blood transfusion. Obstetric patients with severe pre-eclampsia are uniquely susceptible due to a "two-hit" mechanism, where the underlying inflammatory
Puti Fajri Lestari, Pom Harry Satria
doaj   +1 more source

Platelet clotting defects in severe trauma identified by a whole blood microfluidic assay

Transfusion, EarlyView.
Abstract Background Hemorrhage is the leading cause of preventable death in severe trauma, with primary hemostasis relying on platelet‐rich clot formation under high shear flow. This study quantifies the incidence, severity, and heterogeneity of platelet dysfunction in Level I trauma patients.
Gian Rivera Crespo, Jack Killinger, Christopher Bresette, Susan M. Shea, David Ku   +4 more
wiley   +1 more source

Pediatric transfusion camp: Developing, piloting and evaluation of a Canadian national pediatric transfusion medicine curriculum

Transfusion, EarlyView.
Abstract Background Standardized post‐graduate education in pediatric transfusion medicine remains limited. The objective of this study was to adapt an adult transfusion education program, Transfusion Camp, to include pediatric content and assess knowledge improvement in pediatric subspecialty trainees.
Ines Zuna, Valérie Arsenault, Kimmo Murto, Suzanne Beno, MacGregor Steele, Jennifer Young, Sarah Leir, Angela Punnett, Cheryl Peters, Lucille Barcat, Yulia Lin, Casey Kapitany, Sophie Chargé, Teresa Skelton, Lani Lieberman   +14 more
wiley   +1 more source

Synergistic Effect of Anemia and Red Blood Cells Transfusion on Inflammation and Lung Injury

Advances in Hematology, 2012
Anemia and resultant red blood cell transfusion may be associated with adverse long-term clinical outcomes. To investigate the mechanism(s) responsible, we profiled inflammatory biomarkers and circulating levels of the bioactive lysophospholipid mediator
Anping Dong, Manjula Sunkara, Manikandan Panchatcharam, Abdel Salous, Samy Selim, Andrew J. Morris, Susan S. Smyth   +6 more
doaj   +1 more source

Embracing complexity in transfusion research

Vox Sanguinis, EarlyView.
Abstract Complexity science investigates how complex systems behave and how we interact with them. Its implementation in clinical transfusion research is limited, even though human cells, organ systems, bodies, hospitals and blood supply systems are all examples of complex systems.
S. F. Fustolo‐Gunnink
wiley   +1 more source

Acute Lung Injury during Antithymocyte Globulin Therapy for Aplastic Anemia

Canadian Respiratory Journal, 2009
The case of a 33-year-old man with aplastic anemia who experienced recurrent episodes of hypoxemia and pulmonary infiltrates during infusions of antithymocyte globulin (ATG) is described.
Ewan Christopher Goligher, Christine Cserti-Gazdewich, Meyer Balter, Vikas Gupta, Joseph E Brandwein   +4 more
doaj   +1 more source

Outcomes and Surgical Management of Malignant Rhabdoid Tumor of the Kidney: A Report From the Pediatric Surgical Oncology Research Collaborative

Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.
ABSTRACT Purpose Malignant rhabdoid tumor of the kidney (MRTK) is a rare, aggressive tumor seen in young children. The optimal timing of resection for locally advanced tumors is not well‐defined. The purpose of this study is to evaluate modern oncologic outcomes and the impact of surgical timing. Methods A multicenter retrospective review was performed
Hannah N. Rinehardt, Elisabeth T. Tracy, Anghela Paredes, Catherine Beckhorn, Harold J. Leraas, Joseph Fusco, Katlyn G. McKay, Nelly‐Ange T. Kontchou, Zachary J. Kastenberg, David W. Hoyt, Jonathan Roach, Emily K. Myers, Nicholas G. Cost, Bhargava Mullapudi, Charles R. Marchese, Amanda R. Jensen, Timothy B. Lautz, Michela Carter, Roshni Dasgupta, John Lundstedt, Joseph G. Brungardt, Lindsay Talbot, Andrew M. Davidoff, Andrew J. Murphy, Jennifer H. Aldrink, Sara Mansfield, Nelson Piche, Annie Le‐Nguyen, Dave R. Lal, Brian T. Craig, Jennifer M. Schuh, Barrett P. Cromeens, Sindhu Mannava, Shannon Castle, Adriana Lopez, Kelsey Mello, Joshua Short, Robin T. Petroze, Shay Rajavel, Grace R. Thompson, Peter Mattei, David H. Rothstein, Elizabeth Fialkowski, Kathryn Fowler, Nathan Martchenke, Barrie S. Rich, Richard D. Glick, Erin G. Brown, Kathleen Doyle, Paige Abril, Natashia Seemann, Jacob Davidson, Claire A. Wilson, Hau D. Le, Devashish Joshi, Michael Stellon, Tamer Ahmed, Alexandra Dimmer, Peter F. Ehrlich, Maya Hammoud, Keyonna Williams, Christa N. Grant, Merit Gorgy, Stephanie F. Polites, Julia Debertin, Danielle B. Cameron, Alyssa Stetson, Eugene S. Kim, William G. Lee, Aaron Barkhordar, Mary Austin, Brian A. Coakley, Anastasia Kahan, Joseph T. Murphy, Michael Pitonak, Chloé Boehmer, Marcus M. Malek   +76 more
wiley   +1 more source