CD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis
A population of splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. Abstract Background and Aims Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression.
Shaoying Zhang +18 more
wiley +1 more source
Transfusion-related acute lung injury (TRALI): a retrospective review of reported cases in Queensland, Australia over 20 years. [PDF]
BACKGROUND: Transfusion-related acute lung injury (TRALI) is a rare but potentially fatal transfusion reaction. An effective haemovigilance programme is important in implementing successful and targeted risk reduction strategies.
Sivakaanthan A +7 more
europepmc +2 more sources
Acute transfusion reactions can manifest in many forms including acute hemolytic transfusion reaction, allergic reaction and transfusion-related acute lung injury.
Magdielis Gregory Rivera +11 more
doaj +1 more source
Prospective Study on the Clinical Course and Outcomes in Transfusion-Related Acute Lung Injury* [PDF]
ObjectiveTransfusion-related acute lung injury is the leading cause of transfusion-related mortality. A prospective study using electronic surveillance was conducted at two academic medical centers in the United States with the objective to define the ...
Gropper, Michael A +21 more
core +1 more source
Transfusion related acute lung injury (TRALI) [PDF]
A 50-year-old male presented for a Whipple's procedure to excise a pancreatic lesion. Massive transfusion of packed cells and fresh frozen plasma was required. Towards the end of the procedure, the patient developed sudden onset of frank pulmonary oedema and hypotension.
G, Teague, A, Hughes, D, Gaylard
openaire +5 more sources
Transfusion-related acute lung injury (TRALI) in post-partum bleeding patient: A case report
Transfusion-related acute lung injury (TRALI) is a rare but fatal complication of blood transfusion. However, it is frequently under-reported and not diagnosed.
Maulydia Maulydia +3 more
doaj +1 more source
Two septic transfusion reactions presenting as transfusion-related acute lung injury from a split plateletpheresis unit. [PDF]
ObjectivesWe report two simultaneous cases of Staphylococcus aureus sepsis initially consistent with and diagnosed as transfusion-related acute lung injury.
Weiskopf, Richard B +5 more
core +1 more source
Mirasol pathogen reduction technology treatment of human whole blood does not induce acute lung injury in mice. [PDF]
In resource-limited settings and in the military theater, fresh human whole blood is commonly transfused, but infectious risks are a concern. Sophisticated molecular testing for potential infectious agents in the whole blood is often unavailable.
Beñat Mallavia +4 more
doaj +1 more source
TRALI: A fatal risk of blood transfusion in postpartum hemorrhage - the last straw phenomenon
Résumé La Transfusion-Related Acute Lung Injury (TRALI) est une complication potentiellement grave associée à la transfusion sanguine. Elle se caractérise par une insuffisance respiratoire aiguë qui survient généralement dans les six heures suivant ...
Rachida Mansouri, Abdelhamid Sadi
doaj +1 more source
Targeting Transfusion-Related Acute Lung Injury: The Journey From Basic Science to Novel Therapies
Objectives: Transfusion-related acute lung injury is characterized by the onset of respiratory distress and acute lung injury following blood transfusion, but its pathogenesis remains poorly understood.
Wolfgang M. Kuebler +11 more
core +2 more sources

