Results 71 to 80 of about 30,392 (225)
Abstract Solid organ transplant is associated with high rates of anaemia and transfusion, but there is little comparative data on interventions such as erythropoietin‐stimulating agents (ESAs) and intravenous (IV) iron. We conducted a systematic review examining the association of ESAs and IV iron with outcomes in adults undergoing solid organ ...
Frank Lee +13 more
wiley +1 more source
A Teenage Girl with Acute Dyspnea and Hypoxemia during Red Blood Cell Transfusion
Transfusion-related acute lung injury (TRALI) can cause morbidity and mortality. We present the case of teenager who developed dyspnea and hypoxemia few hours after red cell transfusion.
U. Pandee, P. Tanpowpong, P. Thongpo
doaj +1 more source
Abstract Background Immunomodulatory consequences of transfusion, known as transfusion‐related immune modulation (TRIM), impact patients but are not captured by hemovigilance systems. This study's objective is to explore TRIM impacts of production changes made by the blood supplier. Methods We included all transfused and non‐transfused adult inpatients
S. Ning +15 more
wiley +1 more source
Abstract Background The storage of red blood cells (RBCs) is essential for transfusion but leads to storage lesions that compromise RBC quality and increase the risk of transfusion‐related adverse effects, including allergic transfusion reactions (ATRs). Understanding storage‐induced metabolic change is crucial for enhancing transfusion safety.
Gürkan Bal +5 more
wiley +1 more source
Platelet transfusion—the new immunology of an old therapy
Platelet transfusion has been a vital therapeutic approach in patients with hematologic malignancies for close to half a century. Randomized trials show that prophylactic platelet transfusions mitigate bleeding in patients with acute myeloid leukemia ...
Moritz eStolla +7 more
doaj +1 more source
Exploring the immunomodulatory impacts of blood manufacturing consolidation
Abstract Introduction The immunomodulatory consequences of blood transfusion, known as transfusion‐related immune modulation (TRIM), are often not captured by hemovigilance systems. Changes to blood product manufacturing processes may impact patient outcomes.
Amanda Kauffman +11 more
wiley +1 more source
Endothelial thrombomodulin—Its role in trauma‐induced coagulopathy
Abstract Background Trauma‐induced coagulopathy (TIC) describes a complex set of coagulation changes affecting severely injured patients. The thrombomodulin‐protein C axis is central to the evolution of TIC. Soluble thrombomodulin (sTM) levels are elevated after injury and predict poor clinical outcomes.
Jeries Abu‐Hanna +7 more
wiley +1 more source
Abstract Introduction Recent studies have linked trauma patient outcomes to the plasma donor's sex, with premenopausal females associated with improved survival and lower organ failure. Currently, green‐colored plasma (due to oral contraceptive use) is removed from the donor pool. We set out to evaluate the hemostatic potential of green plasma.
Samantha C. Redden +6 more
wiley +1 more source
Transfusion Related Acute Lung Injury -A Case Report
Transfusion related acute lung injury (TRALI) is a rare but life threatening complication of blood transfusion which is being increasingly recognized. It is caused by cross reaction between donor antibodies and host leucocytes or between donor leucocytes
Anamika +3 more
doaj
Neutrophil‐reactive autoantibodies in blood donors: Can we expect TRALI?
Abstract Background Transfusion‐related acute lung injury (TRALI) is a clinical condition characterized by acute non‐cardiogenic pulmonary edema during or after transfusion. Despite several mitigation strategies, TRALI remains a leading cause of transfusion‐related deaths.
Stefanie Jehle +7 more
wiley +1 more source

