Results 141 to 150 of about 332,553 (322)
PLASTIC SURGERY OF BLOOD-VESSELS AND DIRECT TRANSFUSION OF BLOOD [PDF]
Isaac Levin
openalex +1 more source
Alloimmunization among transfusion-dependent thalassemia patients
Background: Thalassemia is a common hemoglobin disorder in Iran and one of the major public health problems. Although blood transfusions are lifesavers for thalassemia patients, they may be associated with some complications especially erythrocyte ...
Sadeghian Mohammad+6 more
doaj
Transfusions of packed red blood cells in the pathology of newborn
Sick newborns are at present the largest group of patients receiving blood products. Therefore packed red blood cells transfusion is one of the most common procedures performed in Intensive Care Units.
Paulina Trojanowska+5 more
doaj
Targeted Therapies in Myelofibrosis: Present Landscape, Ongoing Studies, and Future Perspectives
ABSTRACT Myelofibrosis (MF) is a myeloproliferative neoplasm that is accompanied by driver JAK2, CALR, or MPL mutations in more than 90% of cases, leading to constitutive activation of the JAK–STAT pathway. MF is a multifaceted disease characterized by trilineage myeloid proliferation with prominent megakaryocyte atypia and bone marrow fibrosis, as ...
Giuseppe G. Loscocco, Paola Guglielmelli
wiley +1 more source
Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann+25 more
wiley +1 more source
A PRACTICAL METHOD FOR DETERMINING THE AMOUNT OF BLOOD PASSING OVER DURING DIRECT TRANSFUSION [PDF]
Eva Libman
openalex +1 more source
ABSTRACT Allogeneic hematopoietic stem‐cell transplantation (HCT) remains the only potentially curative therapy for patients with myelodysplastic neoplasms (MDS) and myelofibrosis (MF) and is the standard care for eligible patients with higher‐risk disease. Despite significant advancements, both diseases pose unique challenges due to their clinical and
Nico Gagelmann, Nicolaus Kröger
wiley +1 more source
CD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis
A population of splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. Abstract Background and Aims Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression.
Shaoying Zhang+18 more
wiley +1 more source