Results 21 to 30 of about 884,981 (343)

A Phase 3 Trial of Luspatercept in Patients with Transfusion-Dependent β-Thalassemia.

New England Journal of Medicine, 2020
BACKGROUND Patients with transfusion-dependent β-thalassemia need regular red-cell transfusions. Luspatercept, a recombinant fusion protein that binds to select transforming growth factor β superfamily ligands, may enhance erythroid maturation and reduce
M. Cappellini, V. Viprakasit, A. Taher, P. Georgiev, K. Kuo, T. Coates, E. Voskaridou, H. Liew, Idit Pazgal-Kobrowski, G. Forni, S. Perrotta, A. Khelif, A. Lal, A. Kattamis, E. Vlachaki, R. Origa, Y. Aydinok, M. Bejaoui, P. Ho, L. Chew, P. Bee, Soo-Min Lim, Meng-Yao Lu, A. Tantiworawit, P. Ganeva, L. Gercheva, Farrukh T Shah, E. Neufeld, A. Thompson, A. Laadem, J. Shetty, J. Zou, Jennie Zhang, D. Miteva, T. Zinger, P. Linde, M. Sherman, O. Hermine, J. Porter, A. Piga, Believe Investigators   +40 more
semanticscholar   +1 more source

Effectiveness of blood transfusions and risk factors for mortality in children aged from 1 month to 4 years at the Bon Marche Hospital, Bunia, Democratic Republic of Congo [PDF]

, 2012
Objective  To assess the effectiveness of blood transfusions in a hospital of north-eastern Democratic Republic of the Congo. Methods  Prospective study of children admitted for severe anaemia.
Akech, Calis, Dalmas, Evans, Hassall, Madjdpour, Marcucci, Molyneux, Pedro, Phiri   +9 more
core   +2 more sources

Transfusion strategies in non-bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine

Intensive Care Medicine, 2020
Objective To develop evidence-based clinical practice recommendations regarding transfusion practices in non-bleeding, critically ill adults. Design A task force involving 13 international experts and three methodologists used the GRADE approach for ...
A. Vlaar, S. Oczkowski, S. D. Bruin, M. Wijnberge, M. Antonelli, C. Aubron, P. Ariés, J. Duranteau, N. Juffermans, J. Meier, G. Murphy, R. Abbasciano, M. C. Müller, Akshay Shah, Akshay Shah, A. Perner, Sofie Rygaard, T. Walsh, G. Guyatt, J. Dionne, M. Cecconi   +20 more
semanticscholar   +1 more source

Perioperative transfusion analysis and blood ordering schedule update for total knee arthroplasty

Zhongguo shuxue zazhi, 2023
Objective To investigate the perioperative rate of allogeneic red blood cell (RBC) transfusion in patients who underwent total knee arthroplasty (TKA) and its risk factors, and to identify its cross-match to transfusion ratio (C∶T ratio).
Manjiao MA, Yuelun ZHANG, Lulu MA, Jia GAN, Yuguang HUANG, Xisheng WENG, Jin LIN, Jin JIN, Wenwei QIAN   +8 more
doaj   +1 more source

Anaemia and blood transfusion in African children presenting to hospital with severe febrile illness [PDF]

, 2015
BACKGROUND: Severe anaemia in children is a leading cause of hospital admission and a major cause of mortality in sub-Saharan Africa, yet there are limited published data on blood transfusion in this vulnerable group.
Akech, SO, Babiker, AG, Crawley, J, Engoru, C, George, EC, Gibb, DM, Kiguli, S, Levin, M, Maitland, K, Mtove, G, Nyeko, R, Olupot-Olupot, P, Opoka, RO, Reyburn, H   +13 more
core   +1 more source

Prion diseases are efficiently transmitted by blood transfusion in sheep [PDF]

, 2008
The emergence of variant Creutzfeld-Jakob disease, following on from the bovine spongiform encephalopathy (BSE) epidemic, led to concerns about the potential risk of iatrogenic transmission of disease by blood transfusion and the introduction of costly ...
Andréoletti, Angela Chong, Bishop, Brown, Castilla, Clarke, Fiona Houston, Goldmann, Goldmann, Goldmann, González, González, Gregori, Gregori, Hadlow, Hewitt, Hill, Hilton, Houston, Houston, Hunter, Ironside, James Foster, Jeffrey, Jeffrey, Jeffrey, Kirby, Llewelyn, Lorenzo González, Martin Jeffrey, Mead, Nora Hunter, O'Rourke, Peden, Sandra McCutcheon, Saá, Schreuder, Silvia Sisó, Sisó, Valleron, van Keulen, Wilfred Goldmann, Will, Wroe   +43 more
core   +1 more source

Paediatric transfusion [PDF]

Vox Sanguinis, 2001
Paediatric transfusion encompasses a wide range of clinical circumstances including the consideration of maternal antibodies, the changing nature of the transfusion recipient with respect to growth and development, and the management of inherited conditions which if optimally treated in early life may have problems which are delayed or less severe in ...
J, Simpson, S, Kinsey
openaire   +2 more sources

Monitoring of the Blood Plasma Redox Potential During Plasma Quarantining (Preliminary Report)

Общая реаниматология, 2019
The purpose of the study: to identify significant changes in the electrochemical properties of quarantine-stored blood plasma and of donor blood plasma during its in vitro mixing with quarantined plasma in order to assess the effect of transfusion of ...
I. V. Goroncharovskaya, V. B. Khvatov, A. K. Evseev, A. K. Shabanov, M. M. Goldin, S. S. Petrikov   +5 more
doaj   +1 more source

Development and Evaluation of a Serum Transfusion Process in the Thorny Devil Stick Insect (Eurycantha calcarata)

Frontiers in Veterinary Science, 2022
The thorny devil stick insect (Eurycantha calcarata) is a common invertebrate maintained under human care. Blood (hemolymph) transfusions are a widely used therapeutic tool in other species, but investigation in terrestrial arthropods remains scarce ...
Taylor M. Gregory, Ashlyn C. Heniff, Melinda A. Gorges, Andrew W. Lathan, Gregory A. Lewbart, Julie A. Balko   +5 more
doaj   +1 more source

Microfluidic flow chambers using reconstituted blood to model hemostasis and platelet transfusion in vitro [PDF]

, 2016
Blood platelets prepared for transfusion gradually lose hemostatic function during storage. Platelet function can be investigated using a variety of (indirect) in vitro experiments, but none of these is as comprehensive as microfluidic flow chambers.
Compernolle, Veerle, Devloo, Rosalie, Feys, Hendrik, Van Aelst, Britt, Vandekerckhove, Philippe   +4 more
core   +2 more sources