Results 171 to 180 of about 60,792 (253)

Engineering of the Flavone Rutinoside Biosynthetic Pathway Enables Production of Diosmin, a Venoactive Compound in Solanum lycopersicum and Nicotiana tabacum

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Diosmin is often used as a dietary supplement, and it is sometimes used to make phlebotropic drugs for venous diseases. Traditionally, diosmin is obtained by the dehydrogenation of the flavanone glycoside hesperidin through chemical semisynthesis.
Qianle Zhang   +5 more
wiley   +1 more source

Why Paternalism Is Wrong (When It Is Wrong)

open access: yesPhilosophy and Phenomenological Research, EarlyView.
ABSTRACT This paper proposes a novel reinterpretation of the familiar, if inchoate, thought that paternalism offends against an ideal of personal sovereignty. The central idea is that (competent) persons have a particular kind of normative power. Just as each of us has the right to control how others are permitted to use our bodies or property, we each
Jonathan Parry
wiley   +1 more source

Inflammation and mechanical force‐induced bone remodeling

open access: yesPeriodontology 2000, EarlyView.
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon   +6 more
wiley   +1 more source

HHV‐8/KSHV in Solid Organ Transplantation: Current Gaps of Knowledge and Future Directions

open access: yesTransplant Infectious Disease, EarlyView.
Risk mitigation strategies, including donors/recipients screening, DNAemia monitoring in recipients at risk, CNI‐to‐mTOR inhibitors switch, antivirals, and rituximab for KICS, may mitigate the impact of HHV‐8/KSHV infection in SOT. This review provides an update on KICS, identifies research gaps, and summarizes advances in screening and management ...
Alessandra Mularoni   +9 more
wiley   +1 more source

Evaluating the effects of a hospital utilisation improvement program on platelet transfusions: A pre‐post study

open access: yesTransfusion Medicine, EarlyView.
Abstract Background Annually millions of platelet concentrate (PC) are transfused worldwide. The decision regarding PC transfusion is often complex; therefore, the implementation of a hospital programme designed to streamline and facilitate the decision‐making process is beneficial. Such a programme helps standardise transfusion practices, ensures that
Piotr F. Czempik   +2 more
wiley   +1 more source

Perinatal clinical management of a rare ABh variant blood group

open access: yesTransfusion Medicine, EarlyView.
Abstract Background The H antigen, precursor of the A and B blood groups, is a high‐prevalence antigen. Very few H antigen‐negative (H−) blood donors are available in the United Kingdom. Case Presentation We present the case of a second pregnancy in a 28‐year‐old woman with the very rare ABh phenotype, and the presence of anti‐H, anti‐A and anti‐B ...
Aritri Mandal   +4 more
wiley   +1 more source

Heart rate changes after phlebotomy in polycythaemia vera and healthy donors: An observational case‐crossover pilot study

open access: yesTransfusion Medicine, EarlyView.
Abstract Background Haemoglobin plays a crucial role in oxygen transport, and any acute deviation will trigger compensatory hemodynamic functions. While the consequences of anaemia are well documented, the effects of haemoglobin reduction in individuals without anaemia remain less explored. Patients with polycythaemia vera and healthy blood donors, who
Rik P. B. Tonino   +3 more
wiley   +1 more source

Comparative evaluation of blood component preparation with the top‐and‐top and top‐and‐bottom methods: A change in Uruguay

open access: yesTransfusion Medicine, EarlyView.
Abstract Background Hospital de Clínicas, in conjunction with the Universidad de la República UDELAR in Uruguay, evaluated the quality of blood components after separation with a top‐and‐bottom (TB) system, comparing it with the top‐and‐top (TT) system and verifying compliance with local and international standards. Study Design and Methods Whole blood
Natalia Méndez Acosta   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy