Results 21 to 30 of about 1,360,432 (251)

Blood transfusion reactions and risk of acute kidney injury and major adverse kidney events [PDF]

Journal of Nephrology
Jonathan S Chávez-Iñiguez, Gael Chávez-Alonso, Alejandro Martinez Gallardo-Gonzalez   +2 more
exaly   +2 more sources

Appropriateness of red blood cell use in China in the last thirteen years: A systematic review

Heliyon, 2019
Objective: To determine both the rates of appropriate red blood cells (RBCs) use in China and where inappropriate use is particularly prevalent. Background: In China, obtaining the comprehensive picture in unnecessary RBCs transfusion is helpful for ...
Yujie Kong, Xiangming Wang, Yonghua Yin, Xue Tian, Ling Li, Jue Wang, Li Tian, Ning Song, Zhong Liu   +8 more
doaj   +1 more source

Transfusion Reactions in Pediatric Patients: An Analysis of 5 Years of Hemovigilance Data From a National Center for Children's Health in China

Frontiers in Pediatrics, 2021
Objective: This study aimed to describe transfusion reactions of pediatric patients from a National Center for Children's Health in China and to examine reaction incidents, reaction types by blood transfusion, and the associated blood products resulting ...
Kai Guo, Xiaohuan Wang, Huimin Zhang, Mengjian Wang, Shanshan Song, Shuxuan Ma   +5 more
doaj   +1 more source

Transfusion Related Emergencies [PDF]

, 2016
Audience: This exercise is appropriate for all emergency medicine learners (residents and medical students) and learners from other specialties (internal medicine, family medicine, anesthesia). Introduction: About 85 million red blood cell units are
Min-Ha Tran, Megan Boysen Osborn, Tran, Min-Ha, Osborn, Megan Boysen, Osborn, Megan Boysen ; Tran, Min-Ha   +4 more
core   +1 more source

Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy

Hepatology, EarlyView., 2022
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann, Marti Cabanes‐Creus, Moritz Ertelt, Renina Gale Navarro, Julie Lucifora, Qinggong Yuan, Karin Nien‐Huber, Ahmed Abdelrahman, Xuan‐Khang Vu, Liang Zhang, Ann‐Christin Franke, Christian Schmithals, Albrecht Piiper, Annabelle Vogt, Maria Gonzalez‐Carmona, Jochen T. Frueh, Evelyn Ullrich, Philip Meuleman, Steven R. Talbot, Margarete Odenthal, Michael Ott, Erhard Seifried, Clara T. Schoeder, Joachim Schwäble, Leszek Lisowski, Hildegard Büning   +25 more
wiley   +1 more source

Transfusion strategies for patients in pediatric intensive care units [PDF]

, 2007
Background: The optimal hemoglobin threshold for erythrocyte transfusions in critically ill children is unknown. We hypothesized that a restrictive transfusion strategy of using packed red cells that were leukocyte-reduced before storage would be as safe
Gauvin, France, Meert, Kathleen, Lacroix, J, Hume, HA, Lacroix, Jacques, Hutchinson, James S., Toledano, BJ, Peters, Mark J, Joffe, Ari, Collet, Jean-Paul, Gauvin, F, Ducruet, T, Hurne, Heather A., Robillard, P, Biarent, Dominique, Peters, MJ, Hutchison, JS, Toledano, Baruch J., Hebert, PC, Joffe, A, Biarent, D, Ducruet, Thierry, Collet, J-P, Meert, K, Tucci, Marisa, Robillard, Pierre, Hebert, Paul C., Tucci, M   +27 more
core   +1 more source

CD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis

Hepatology, EarlyView., 2022
A population of splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. Abstract Background and Aims Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression.
Shaoying Zhang, Dan Wan, Mengchen Zhu, Guihu Wang, Xurui Zhang, Na Huang, Jian Zhang, Chongyu Zhang, Qi Shang, Chen Zhang, Xi Liu, Fanfan Liang, Chunyan Zhang, Guangyao Kong, Jing Geng, Libo Yao, Shemin Lu, Yongyan Chen, Zongfang Li   +18 more
wiley   +1 more source

Pattern of Adverse Transfusion Reactions in Acute Leukaemia Treated with Different Types of Blood Component Therapy in a Tertiary Care Hospital

Haematology Journal of Bangladesh, 2020
Background: Transfusion of blood products is one of the principle components of supportive management in patients with acute leukaemia. Objective: The purpose of this study was to observe the pattern of adverse transfusion reactions (ATR) in acute ...
Md. Jaki Yamani, Md. Golzar Hossain, Md. Ashraful Haque Chowdhury, Md. Imran Hossain, Mohammed Murad Hossain, Md. Rafiquzzaman Khan, Md. Salahuddin Shah, Md. Abdul Aziz, A B M Yunus   +8 more
doaj   +1 more source

Transfusion reactions in pediatric and adolescent young adult haematology oncology and immune effector cell patients

EClinicalMedicine, 2020
Background: Active surveillance for transfusion reactions is critically important among pediatric patients undergoing chemotherapy. Among pediatric-adolescent-young-adult (AYA) hematology/oncology patients, who have been typically excluded from ...
Mira A. Kohorst, Sajad J. Khazal, Priti Tewari, Demetrios Petropoulos, Benjamin Mescher, Jian Wang, Kris M. Mahadeo, James M. Kelley   +7 more
doaj   +1 more source

Anti-platelet factor 4/polyanion antibodies mediate a new mechanism of autoimmunity

Nature Communications, 2017
Antibodies against the platelet factor 4 (PF4) support bacterial host defence but in some cases may lead to heparin-induced thrombocytopenia (HIT).
Thi-Huong Nguyen, Nikolay Medvedev, Mihaela Delcea, Andreas Greinacher   +3 more
doaj   +1 more source