Results 81 to 90 of about 60,792 (253)

Hemophilia A: An Ideal Disease for Prenatal Therapy

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada, Anthony Atala, Graça Almeida‐Porada   +2 more
wiley   +1 more source

Recognition, Investigation and Management of Acute Transfusion Reactions : Consensus guidelines for Oman

Sultan Qaboos University Medical Journal, 2014
The recognition and management of transfusion reactions (TRs) are critical to ensure patient safety during and after a blood transfusion. Transfusion reactions are classified into acute transfusion reactions (ATRs) or delayed transfusion reactions, and ...
Arwa Z. Al-Riyami, Sabria Al-Hashmi, Zainab Al-Arimi, Louis D. Wadsworth, Abdulhakim Al-Rawas, Murtadha Al-Khabori, Shahina Daar   +6 more
doaj   +2 more sources

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

Septic Transfusion Reactions Involving Burkholderia cepacia Complex: A Review. [PDF]

Microorganisms, 2023
Salamanca-Pachon M, Guayacan-Fuquene NI, Garcia-Otalora MA.   +2 more
europepmc   +1 more source

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

Prenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear, Beltran Borges, Billie R. Lianoglou, Tony Lum, Emma Canepa, Jennifer L. Cohen, Julia E. H. Brown, Akos Herzeg   +7 more
wiley   +1 more source

Feline blood donation via cephalic intravenous catheter: A novel method

Veterinary Record, EarlyView.
Abstract Background Feline jugular blood donation requires heavy sedation or a very compliant cat. Donation using an intravenous catheter requires less restraint and potentially decreases stress. Methods This was an observational study of feline blood donors at a veterinary hospital between February and June 2023.
Charlotte Russo, Karen Humm
wiley   +1 more source

Multiplex visual nucleic acid detection via isothermal cascaded transcription of fluorescent RNA aptamers

VIEW, EarlyView.
(1) Existing multiplex nucleic acid detection struggles to combine high sensitivity, visual readout, and instrument‐free use, which is vital for rapid infection and antibiotic resistance diagnosis. (2) We developed MAGIC, integrating isothermal cascaded amplification and fluorescent RNA aptamer transcription, achieving 10 aM sensitivity, 100% accuracy ...
Yu Tang, Na Luo, Binbin Xie, Jie Luo, Yaling Yuan, Junjie Fan, Zhiyong Liu, Haiyan Gao, Ming Chen, Kai Chang   +9 more
wiley   +1 more source

A1vB Genotype Wwith Weak A Antigen Expression: Resolution of an ABO Discrepancy Using Serological and Molecular Approaches

The Kaohsiung Journal of Medical Sciences, EarlyView.
Wan‐Hua Yang, Fen‐Cing Liou
wiley   +1 more source

The Feasibility and Safety of Prehospital Whole Blood Administration for Patients in Hemorrhagic Shock in Isolated Regions of Colorado: Assessment of the First 6 Months

World Journal of Surgery, EarlyView.
The aim of this pilot study is to summarize evidence from the implementation of prehospital whole blood programs in rural Colorado with focus on the feasibility and safety of whole blood in rural areas with prolonged transport times to definitive care.
Matthew Branney, Sydney Mattox, John Lynch, Scott Branney, Laura Harwood, Rebecca Ryznar, Zsolt J. Balogh   +6 more
wiley   +1 more source

Transfusion reactions associated with COVID-19 convalescent plasma in outpatient clinical trials. [PDF]

Transfusion, 2023
Huaman MA, Raval JS, Paxton JH, Mosnaim GS, Patel B, Anjan S, Meisenberg BR, Levine AC, Marshall CE, Yarava A, Shenoy AG, Heath SL, Currier JS, Fukuta Y, Blair JE, Spivak ES, Petrini JR, Broderick PB, Rausch W, Cordisco M, Hammel J, Greenblatt B, Cluzet VC, Cruser D, Oei K, Abinante M, Hammitt LL, Sutcliffe CG, Forthal DN, Zand MS, Cachay ER, Kassaye SG, Ram M, Wang Y, Das P, Lane K, McBee NA, Gawad AL, Karlen N, Ford DE, Laeyendecker O, Pekosz A, Klein SL, Ehrhardt S, Lau B, Baksh SN, Shade DM, Casadevall A, Hanley DF, Ou J, Gniadek TJ, Ziman A, Shoham S, Gebo KA, Bloch EM, Tobian AAR, Sullivan DJ, Gerber JM.   +57 more
europepmc   +1 more source