Results 151 to 160 of about 42,328 (214)

Cross-species transfer of sensor and helper NLR confers resistance to black rot in Brassica oleracea. [PDF]

open access: yesMol Hortic
Deng S   +9 more
europepmc   +1 more source

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell   +3 more
wiley   +1 more source

In silico analysis of putative interactions identifies fibroblasts as hubs for cell–cell communication during early regeneration of the zebrafish heart

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The zebrafish heart regenerates upon injury. During injury response, fibroblasts and endothelial cells accumulate at the site of damage, and cardiomyocyte cell cycle reentry allows cardiac muscle regrowth. It is relevant to understand how the different cell types communicate with each other to coordinate regeneration.
João A. S. Carvalho   +6 more
wiley   +1 more source

Anterior cingulate cortex neuron subtypes differentially regulate seizures

open access: yesEpilepsia, EarlyView.
Abstract Objective This study aimed to investigate the regulatory roles of distinct neuronal subtypes within the anterior cingulate cortex (ACC) in acute seizures and to identify cell type‐specific mechanisms underlying seizure modulation in this region. Methods Acute seizure models were established in mice via pentylenetetrazol injection.
Ziqian Yan   +12 more
wiley   +1 more source

Triggered Calcium Lightning Programs Cochlear Development

open access: yesExploration, EarlyView.
Summary: Before the onset of hearing, the developing inner ear generates spontaneous calcium signals that are thought to guide maturation. In this study, we discovered a rapid and widespread calcium flash—dubbed “Ca2+ lightning”—originating from supporting cells beneath the sensory hair cells, which triggers coordinated calcium waves across the entire ...
Qiang Ma   +13 more
wiley   +1 more source

Genome Editing in Solanaceae: Harnessing CRISPR-Cas Technology for Precision Crop Improvement. [PDF]

open access: yesPlants (Basel)
Thakur V   +12 more
europepmc   +1 more source

Immunomodulatory Effect of Tilapia (Oreochromis niloticus) Scale Gelatin Peptides in RAW264.7 Macrophages and Caenorhabditis elegans

open access: yesFood Safety and Health, EarlyView.
ABSTRACT Currently, small‐molecular‐weight collagen peptides are a research hotspot in functional factor development due to their high bioavailability and diverse bioactivities. In this study, gelatin was extracted from tilapia (Oreochromis niloticus) scales by hot water extraction, followed by pepsin hydrolysis and ultrafiltration to obtain the < 3 ...
Ya‐ru Liu   +5 more
wiley   +1 more source

Anti‐Inflammatory Effects of Punicic Acid and Its Molecular Mechanisms in RAW264.7 Cells and Zebrafish

open access: yesFood Safety and Health, EarlyView.
Punicic acid (PA) was enriched and purified from PSO by molecular distillation with significant anti‐inflammatory activity to RAW264.7 cells, as well as to zebrafish. Anti‐inflammatory mechanism involved regulating NF‐κB and MAPK signaling pathways. ABSTRACT Punicic acid (PA) is the main fatty acid in pomegranate seeds, which shows multiple biological ...
Mengqi Zhang   +8 more
wiley   +1 more source

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