Results 71 to 80 of about 42,328 (214)

Chronic HBV Infection Disrupts CCL5‐Secreting cNK Cells and Attenuates Liver Accumulation and Activation of DCs and HBV‐Specific T Cells

open access: yesAdvanced Science, EarlyView.
ADORA2A activation suppresses NFκB‐dependent CCL5 production in cNK cells during chronic HBV infection, disrupting intrahepatic DC recruitment and HBV‐specific CD8+ T‐cell differentiation and function. Targeting the ADORA2A/NFκB/CCL5 axis restores antiviral immunity and facilitates HBV clearance.
Ailu Yang   +9 more
wiley   +1 more source

Optimisation of qualitative and semi-quantitative detection of genetically modified crops by PCR

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2009
For qualitative and semi-quantitative detection of genetically modified crops we selected the detection of the frequently used promoter 35S CaMV. To optimise the method we used two commercially available genotypes of maize from the company Monsanto (USA),
Tomáš Vyhnánek, Pavel Hanáček
doaj   +1 more source

Herbicide Metabolic Resistance in Poaceae Plants via the GA‐GID1/DELLA‐DOF2‐P450s Module

open access: yesAdvanced Science, EarlyView.
Plant hormone signaling modulates herbicide resistance in Echinochloa crus‐galli. The GA–DELLA–DOF2 cascade directly activates P450 detoxification genes in two Poaceae species, uncovering a core mechanism of metabolic herbicide resistance. ABSTRACT Barnyard grass (Echinochloa crus‐galli) is one of the world's most important weeds, and the evolution of ...
Junzhi Wang   +6 more
wiley   +1 more source

Approved genetically modified (GM) horticultural plants: A 25-year perspective

open access: yesFolia Horticulturae, 2019
In this review, we present genetically modified (GM) horticultural events that have passed the regulatory process and have been approved for cultivation or food use in different countries.
Baranski Rafal   +2 more
doaj   +1 more source

Disease Occurrence in Transgenic Rice Plant Transformed with Silbene Synthase Gene and Evaluation of Possible Horizontal Gene Transfer to Plant Pathogens

open access: yesResearch in Plant Disease, 2014
Genetic engineering is being used to enhance disease resistance and nutritional value of crops including rice plant. Considering the fast-growing agricultural biotechnology and rapidly increasing global area of transgenic crops, the risk evaluation on ...
Sang-Mi Yu   +5 more
doaj   +1 more source

Aberrant GRP78 Phase Transition Sustains Endothelial IRE1α Signaling and Drives Blood–Brain Barrier Failure in Cerebral Amyloid Angiopathy

open access: yesAdvanced Science, EarlyView.
Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng   +19 more
wiley   +1 more source

Agrofuels and transgenic crops: a couple that promotes the loss of food sovereignty

open access: yesLetras Verdes: Revista Latinoamericana de Estudios Socioambientales, 2013
In order to approach to understanding the threat agrofuels and transgenic crops pose to food sovereignty, this paper revises some statements in relation to the dynamics related to these proposals and the socio–environmental conflicts they generate. Thus,
Milena Espinosa
doaj   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

open access: yesAdvanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie   +12 more
wiley   +1 more source

Efecto ambiental de agroquímicos y maquinaria agrícola en cultivos transgénicos y convencionales de algodón

open access: yesRevista Colombiana de Biotecnología, 2010
Título en inglés: Environmental effects of agrochemicals and agricultural machinery in transgenic and conventional crops cotton Resumen La producción de alimentos se basa en el uso de diferentes tecnologías agrícolas, que pueden derivar en conflictos ...
Giovanni Reyes   +2 more
doaj  

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