Results 171 to 180 of about 1,644,173 (317)

Activation of retrovirus in transgenic mice: association with development of olfactory neuroblastoma [PDF]

, 1990
Kazuhiko Koike, Gregory D. Jay, Janet W. Hartley, Mark D. Schrenzel, Robert Higgins, S H Hinrichs   +5 more
openalex   +1 more source

PM2.5 Induce Endothelial‐Mesenchymal Transition and Cardiac Fibrosis via the NCOA4‐Mediated Ferritinophagy

Advanced Science, EarlyView.
This study primarily reveals that PM2.5‐derived Fe‐containing particles, particularly magnetite, are specifically enriched in the heart. Here, they interact with NCOA4 in endothelial cells, disrupt iron homeostasis by enhancing ferritinophagy, and subsequently trigger the process of EndMT through the NCOA4/KLF5 pathway.
Qinglin Sun, Mengyuan Wang, Lin Liu, Ruiyang Ding, Kanglin Yan, Shiqian Liu, Xiaoke Ren, Qing Xu, Zhiwei Sun, Qian Liu, Yi Yang, Junchao Duan   +11 more
wiley   +1 more source

Rescue of male infertility by human PRSS55 in transgenic mice establishes a contraceptive research model. [PDF]

Sci Rep
Sutton CM, Umezu K, Mashiko D, Ikawa M, Larina IV, Garcia TX, Matzuk MM.   +6 more
europepmc   +1 more source

What are transgenic mice and how will they affect medicine?

, 1986
Milton M. Weiser
openalex   +1 more source

Loss of Hepatic Angiotensinogen Attenuates Diastolic Dysfunction in Heart Failure with Preserved Ejection Fraction

Advanced Science, EarlyView.
Increased hepatic angiotensinogen (AGT) abundance leads to cardiac diastolic dysfunction via the AngII‐independent pathway. Liver‐derived AGT is internalized by LRP2 in cardiac endothelial cells, subsequently contributing to myocardial diastolic dysfunction by suppressing microvascular angiogenesis via inhibiting the GATA2/Pim3 pathway.
Zetao Heng, Min Hong, Zhaocai Zhang, Ximing Ye, Jianan Zhou, Wentao Wu, Jiabing Rong, Yinchuan Xu   +7 more
wiley   +1 more source

Integrin CD103 reveals a distinct developmental pathway of autoreactive thymocytes in TCR transgenic mice. [PDF]

Nat Commun
Liman N, Li C, Luckey MA, Keller HR, Li J, Hajjar W, Wisniewski J, Kruhlak M, Lazarevic V, Park JH.   +9 more
europepmc   +1 more source

Isolation and characterization of renin-expressing cell lines from transgenic mice containing a renin-promoter viral oncogene fusion construct.

, 1990
Curt D. Sigmund, Kaori Okuyama, Julie R. Ingelfinger, Craig A. Jones, John J. Mullins, C Kane, U Kim, Chuanzen Wu, L N Kenny, Youcef M. Rustum   +9 more
openalex   +1 more source

Targeted Expression of the E6 and E7 Oncogenes of Human Papillomavirus Type 16 in the Epidermis of Transgenic Mice Elicits Generalized Epidermal Hyperplasia Involving Autocrine Factors [PDF]

, 1994
Prasert Auewarakul, Lutz Gissmann, Ángel Cid-Arregui   +2 more
openalex   +1 more source

Hepatic CBP/p300 Orchestrate Amino Acid‐Driven Gluconeogenesis through Histone Crotonylation

Advanced Science, EarlyView.
Hepatic CBP/p300 control amino acid‐driven gluconeogenesis by modulating histone crotonylation. This study identifies 2‐aminoadipate (2‐AAA) as a key metabolite that enhances crotonylation and activates amino acid and gluconeogenic gene expression.
Chunxiang Sheng, Tianjiao Li, Hong Lin, Xiaoqin Ma, Feiye Zhou, Mingzhu Li, Yiru Wang, Shushu Wang, Jialin Tan, Junmin Chen, Yulin Yang, Jianmin Liu, Yufang Bi, Jieli Lu, Xiao Wang, Libin Zhou   +15 more
wiley   +1 more source

Calorie restriction delays spontaneous tumorigenesis in p53-knockout transgenic mice.

, 1994
Stephen D. Hursting, Susan N. Perkins, James M. Phang   +2 more
openalex   +1 more source