Results 41 to 50 of about 4,008,952 (354)

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Improvement of pest resistance in transgenic tobacco plants expressing dsRNA of an insect-associated gene EcR. [PDF]

open access: yesPLoS ONE, 2012
The adoption of pest-resistant transgenic plants to reduce yield loss and pesticide utilization has been successful in the past three decades. Recently, transgenic plant expressing double-stranded RNA (dsRNA) targeting pest genes emerges as a promising ...
Jin-Qi Zhu   +8 more
doaj   +1 more source

Removal of a cryptic intron and subcellular localization of green fluorescent protein are required to mark transgenic Arabidopsis plants brightly.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1997
The green fluorescent protein (GFP) from the jellyfish Aequorea victoria is finding wide use as a genetic marker that can be directly visualized in the living cells of many heterologous organisms.
J. Haseloff   +3 more
semanticscholar   +1 more source

Transgenic Plants and Animals

open access: yes, 2023
Transgenic plants and animals represent a frontier that enables us to alter the very fabric of life. Now, scientists can integrate foreign genes into an organism's genome enhance desirable traits, such as increased resistance to pests, improved nutritional content, and greater adaptability to environmental challenges.
openaire   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Drought Tolerance in Transgenic Potato Cultivar IPB CP1 Expressing MmCuZn-SOD Gene

open access: yesHayati Journal of Biosciences
Drought stress induces reactive oxygen species (ROS) accumulation, which is harmful to plant cells. Consequently, it inhibits plant growth and decreases yield. The enzyme superoxide dismutase (SOD), which is encoded by the SOD gene, is the first defence
Musawira   +3 more
doaj   +1 more source

Plant Biotechnology: Transgenic Crops

open access: yes, 2008
Transgenesis is an important adjunct to classical plant breeding, in that it allows the targeted manipulation of specific characters using genes from a range of sources. The current status of crop transformation is reviewed, including methods of gene transfer, the selection of transformed plants and control of transgene expression.
Shewry, P. R.   +2 more
openaire   +3 more sources

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

Overexpression of the Ginkgo biloba dihydroflavonol 4-reductase gene GbDFR6 results in the self-incompatibility-like phenotypes in transgenic tobacco

open access: yesPlant Signaling & Behavior, 2023
Although flavonoids play multiple roles in plant growth and development, the involvement in plant self-incompatibility (SI) have not been reported.
Ning Zhang   +7 more
doaj   +1 more source

Protein Kinase Activity of Phytochrome A Positively Correlates With Photoresponses in Arabidopsis

open access: yesFrontiers in Plant Science, 2021
Plant phytochromes are known as autophosphorylating serine/threonine protein kinases. However, the functional importance of their kinase activity is not fully elucidated.
Quyen T. N. Hoang   +7 more
doaj   +1 more source

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