Results 81 to 90 of about 1,870,386 (304)

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

open access: yesAdvanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou   +6 more
wiley   +1 more source

Genetic engineering of rice for improved agronomic characteristics [PDF]

open access: yes, 2004
This thesis describes the production of three populations of transgenic rice plants using particle bombardment method altered in two main traits: (1) polyamine content and (2) insect pest resistance.
Pham Trung, Nghia, Trung, Nghia Pham
core  

Population-scale laboratory studies of the effect of transgenic plants on nontarget insects

open access: yes, 2001
Studies of the effects of insect-resistant transgenic plants on beneficial insects have, to date, concentrated mainly on either small-scale ‘worst case scenario’ laboratory experiments or on field trials.
Denholm, I.   +14 more
core   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave   +8 more
wiley   +1 more source

Transgenic plants of Petunia hybrida harboring the CYP2E1 gene efficiently remove benzene and toluene pollutants and improve resistance to formaldehyde

open access: yesGenetics and Molecular Biology, 2011
The CYP2E1 protein belongs to the P450 enzymes family and plays an important role in the metabolism of small molecular and organic pollutants. In this study we generated CYP2E1 transgenic plants of Petunia using Agrobacterium rhizogenes K599.
Daoxiang Zhang   +3 more
doaj  

The effects of foreign genes in transgenic Thale cress (Arabidopsis thaliana [PDF]

open access: yes, 1991
Agrobacterium tumefaciens-mediated transformation was used to introduce foreign genes into Arabidopsis thaliana (Thale Cress). Initially a simple marker gene construct (pJIT73) was used to set up the transformation system. Once established, three further
Evans, Katherine Mary, Evans, K.M
core  

Production of transgenic Pinus armandii plants harbouring btCryIII(A) gene

open access: yes, 2010
A synthetic chimeric gene SbtCryIII(A) encoding the insecticidal protein btCryIII(A), was transformed into Pinus armandii embryos and embryogenic calli using Agrobacterium tumefaciens.
Z. Liu   +3 more
core   +1 more source

Ionizable Lipid‐Dependent Optimization of Steroid Lipid Nanoparticles With Tunable Immunomodulatory Properties

open access: yesAdvanced Materials, EarlyView.
A novel engineering strategy that establishes material design principles for incorporating anti‐inflammatory steroids into lipid nanoparticles to reduce LNP‐induced inflammation while retaining mRNA delivery. Results are validated in vitro and in three animal models of inflammation and autoimmunity in vivo.
Ajay S. Thatte   +21 more
wiley   +1 more source

Study on transformation of tobacco plant with flower symmetry gene LjCYC3 in Lotus japonicus

open access: yes浙江大学学报. 农业与生命科学版, 2011
According to LjCYC3 gene controlling flower symmetry in Lotus japonicus, the antisense gene expression vector was constructed, and by using Agrobacterium-mediated transformation of tabacoo with justice-antisense LjCYC3 gene, flower patterns changed in ...
ZHANG Han-ying   +4 more
doaj   +1 more source

Biosafety Evaluation of Transgenic Potatoes: Genc Flow from Transgenic Potatoes

open access: yes, 2011
A potential concern associated with the release of transgenic crops is the risk of gene flow to neighboring crops of the same species or to related species.
Anthony J. Conner
core  

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