Results 221 to 230 of about 332,647 (335)

Unraveling the mystery: How autophagy deficiency in dopaminergic neurons drives human Parkinson's disease. [PDF]

Mol Brain
Noda S, Hattori N.
europepmc   +1 more source

Parasitic Plant–Host Interactions: Molecular Mechanisms and Agricultural Resistance Strategies

Advanced Science, EarlyView.
Parasitic plants devastate global agriculture through sophisticated molecular interactions with host crops. This review synthesizes current understanding of parasitic plant‐host interactions, from strigolactone‐mediated germination and haustorium formation to host defense mechanisms.
Jiayang Shi, Qi Xie, Feifei Yu
wiley   +1 more source

Direct Extracellular Matrix Modulation Attenuates Intestinal Fibrosis via a Fibronectin‐Targeted Approach

Advanced Science, EarlyView.
Fibronectin regulates the extracellular matrix (ECM)–myofibroblast cycle through three key steps: (1) its secretion and assembly by myofibroblasts (inhibited by pUR4); (2) collagen deposition along its scaffold (inhibited by R1R2); and (3) integrin α5β1‐mediated mechanotransduction (inhibited by ATN161).
Wenlong Ma, Siyu Yang, Tengkai Wang, Di Zhang, Hewei Wu, Shichen Fu, Xiaohan Wan, Lixiang Li, Xiuli Zuo, Yanqing Li, Jiaoyang Lu   +10 more
wiley   +1 more source

Atomically Precise Clusterzymes: A Programmable Optoelectronic Platform for Neuroscience

Advanced Science, EarlyView.
Atomically precise clusterzymes, engineered via atomic and ligand design, serve as programmable platforms for neuroscience applications. They demonstrate tailored biocatalysis for neuroinflammation, tunable optical properties for deep‐tissue bioimaging and 3D visualization, and enhanced charge transfer for brain–computer interfaces.
Si Sun, Di Liu, Sufei Zhou, Yang Wang, Hao Wang, Ziliang Zheng, Xiao‐Dong Zhang   +6 more
wiley   +1 more source

Genetic control of seasonal meristem arrest in trees. [PDF]

Proc Natl Acad Sci U S A
Wang J, Liao X, Wu Z, Sane S, Han S, Chen Q, Shi X, Dai X, Klintenäs M, Nilsson O, Ding J.   +10 more
europepmc   +1 more source

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

Advanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian, Sreenidhi Mohanvelu, Sheeja Aravindan, Afsana Parveen Jahir Hussain, Sivasubramani Narayanan, Sabir Salim, Loganayaki Periyasamy, Natarajan Aravindan   +7 more
wiley   +1 more source

MicroRNA169 integrates multiple factors to modulate plant growth and abiotic stress responses. [PDF]

Plant Biotechnol J
Chen X, Chen Z, Fiorentino A, Kuess M, Tharayil N, Kumar R, Leonard E, Noorai R, Hu Q, Luo H.   +9 more
europepmc   +1 more source

Natural Variations of ZmRLR1 Mediate the Root Lodging Resistance of Maize by Regulating Root Ascorbate and Auxin Homeostasis

Advanced Science, EarlyView.
Root lodging severely limits crop yield and quality. We reveal that ZmRLR1, a plasma membrane b‐type cytochrome, regulates lodging resistance in maize through dual roles: modulating intracellular redox balance and functioning as a novel component of clathrin‐mediated endocytosis to influence auxin homeostasis. Moreover, natural variations in the ZmRLR1
Wenshuai Lv, Pengshuai Yan, Huan Chen, Guangxian Li, Yiyue Zhao, Yanhui Chen, Wen‐Xue Li, Qingguo Du   +7 more
wiley   +1 more source

BMP signaling promotes zebrafish heart regeneration via alleviation of replication stress. [PDF]

Nat Commun
Vasudevarao MD, Posadas Pena D, Ihle M, Bongiovanni C, Maity P, Geissler D, Mohammadi HF, Rall-Scharpf M, Niemann J, Mommersteeg MTM, Redaelli S, Happ K, Wu CC, Beisaw A, Scharffetter-Kochanek K, D'Uva G, Malek Mohammadi M, Wiesmüller L, Geiger H, Weidinger G.   +19 more
europepmc   +1 more source

Transcriptional signatures of progressive neuropathology in transgenic tau and amyloid mouse models

, 2019
Isabel Castanho, Tracey K. Murray, Eilís Hannon, Aaron R. Jeffries, Emma Walker, Emma Laing, Hedley Baulf, Joshua Harvey, Andrew D. Randall, Karen Moore, Paul O’Neill, Katie Lunnon, David Collier, Zeshan Ahmed, Michael J. O’Neil, Jonathan Mill   +15 more
openalex   +1 more source