Results 41 to 50 of about 27,839 (297)

Transformation efficiency of Arabidopsis thaliana ecotypes with differential tolerance to submergence stress

open access: yesAll Life, 2022
Submergence stress in plants subjected to flooding is a significant issue in agriculture. Decades of previous research have elucidated many molecular and physiological responses of plants to this stress. Since Arabidopsis thaliana has been established as
Mayra Santiago-Velasco   +5 more
doaj   +1 more source

Cartilage on the Move: Cartilage Lineage Tracing During Tadpole Metamorphosis

open access: yes, 2012
The reorganization of cranial cartilages during tadpole metamorphosis is a set of complex processes. The fates of larval cartilage-forming cells (chondrocytes) and sources of adult chondrocytes are largely unknown.
Brittain, Alison L.   +3 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Enhanced artemisinin yield by expression of rol genes in artemisia annua [PDF]

open access: yes, 2016
Background: Despite of many advances in the treatment of malaria, it is still the fifth most prevalent disease worldwide and is one of the major causes of death in the developing countries which accounted for 584,000 deaths in 2013, as estimated by World
Bonfill Baldrich, Ma. Mercedes   +5 more
core   +3 more sources

Interrelationship between potassium rates and the efficiency of Bt genes in the control of Spodoptera frugiperda

open access: yesPesquisa Agropecuária Brasileira, 2023
The objective of this work was to identify the effect of potassium rates on Bt transgenic resistance and damage caused by Spodoptera frugiperda in corn plants at different developmental stages. The experimental design was a randomized complete block in a
Marcelo Macedo Faria   +5 more
doaj   +1 more source

Characterization of VRC01, a potent and broadly neutralizing anti-HIV mAb, produced in transiently and stably transformed tobacco [PDF]

open access: yes, 2014
The proposed clinical trial in Africa of VRC01, a potent broadly neutralizing antibody (bNAb) capable of neutralizing 91% of known HIV-1 isolates, raises concerns about testing a treatment which will be too expensive to be accessible by the most ...
EMEA   +4 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Genetic and physiological characteristics of CsNPR3 edited citrus and their impact on HLB tolerance

open access: yesFrontiers in Genome Editing
Huanglongbing (HLB) disease, caused by Candidatus Liberibacter asiaticus (CaLas), severely impacts citrus production, and currently, there is no cure. Developing HLB-resistant or tolerant cultivars is crucial, with modifying defense-related genes being a
Trishna Tiwari   +9 more
doaj   +1 more source

Genetic and Transgenic Reagents for Drosophila simulans, D. mauritiana, D. yakuba, D. santomea, and D. virilis

open access: yesG3: Genes, Genomes, Genetics, 2017
Species of the Drosophila melanogaster species subgroup, including the species D. simulans, D. mauritiana, D. yakuba, and D. santomea, have long served as model systems for studying evolution.
David L. Stern   +9 more
doaj   +1 more source

Transgenic Hypericum perforatum [PDF]

open access: yes, 2009
Plant transformation is an important tool with many applications in modern plant biology. Although this technique is primarily used to produce superior crop varieties, it is also being utilized to answer basic questions concerning gene function and regulation in contemporary functional genomics research.
Gregory, Franklin   +2 more
openaire   +3 more sources

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