Results 61 to 70 of about 17,611 (257)
A polêmica sobre os transgênicos: Monsanto vs. MST / The polemic about transgenic: Monsanto vs. MST
Bakhtiniana: Revista de Estudos do Discurso, 2011 RESUMO: Neste trabalho, adotando uma perspectiva discursiva, analisamos alguns aspectos do diálogo que se trava, no Brasil, entre o discurso pró e o anti-transgênicos, procurando evidenciar as relações dialógicas que cada um deles estabelece com outros ...
Anna Flora Brunelli
doaj
Mutant TDP-43 and FUS cause adult-onset, age-dependent paralysis in C. elegans.
, 2012 Transgenics were monitored from the adult stage and scored daily for paralysis. (A) mTDP-43 worms show a rate of progressive paralysis that is greater than transgenics expressing wtTDP-43 ...
J. Alex Parker (148331) +5 more
core +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li +11 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou +6 more
wiley +1 more source
Fisheries and Aquatic Sciences, 2016 Background The transgenic approach using estrogen-responsive regulator in fish has been given much attention as a potential means to detect and/or address estrogen-related aquatic pollutions.
Young Sun Cho, Yoon Kwon Nam
doaj +1 more source
Advanced Healthcare Materials, EarlyView.CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli +8 more
wiley +1 more source
Moving past transgenics – the potential for genomics to open markets in the EU for African agricultural products [PDF]
In 1999 the European Union imposed a moratorium on imports of agricultural products produced using biotechnology based on transgenics. In 2003 the moratorium was replaced by a strict, costly and politicised regime for regulatory approval which is ...
Kerr, William A.
core +1 more source
Ionic Gating of Liquid‐Crystal‐Like Pteridine Assemblies Enables Tunable Light Scattering
Advanced Materials, EarlyView.Tunable optical properties emerge through developmentally regulated ionic gating, which transforms disordered, ultraviolet (UV)‐absorbing organelles into concentrically ordered, liquid‐crystal‐like light scatterers. By integrating analyses of pteridine composition, potassium‐dependent assembly, hierarchical ultrastructure, and optical behavior, the ...
Sourabh Bera +22 more
wiley +1 more source
Advanced Materials, EarlyView.Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol +16 more
wiley +1 more source