Results 201 to 210 of about 4,824 (245)
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“Tissue” transglutaminase in AIDS
Journal of Immunological Methods, 2002Apoptosis or programmed cell death (PCD) is an active process of cellular self-destruction, essential for embryonic development and maintenance of homeostasis of multicellular organisms. Programmed cell death induction can serve as a defence mechanism of the host against intracellular microbes.
Alessandra, Amendola +3 more
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Transglutaminases in mineralized tissues
Frontiers in Bioscience, 2006Bone development and formation during embryogenesis as well as postnatally during bone remodeling is a complex process controlled systemically and locally by hormones, growth factors and matrix molecules. Transglutaminases (TGases) are the protein cross-linking enzymes, which have long been implicated in bone development and formation.
Maria, Nurminskaya, Mari T, Kaartinen
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Transglutaminase 2 and neuroinflammation
Amino Acids, 2014Neuroinflammatory processes seem to play a pivotal role in various chronic neurodegenerative diseases, characterized also by the pathogenetic accumulation of specific protein aggregates. Several of these proteins have been shown to be substrates of transglutaminases, calcium-dependent enzymes that catalyze protein crosslinking reactions.
IENTILE, Riccardo +2 more
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Vitronectin is a substrate for transglutaminases
Biochemical and Biophysical Research Communications, 1988Vitronectin (VN) was found to be a substrate for both plasma transglutaminase (Factor XIIIa) and guinea pig liver transglutaminase (TG). Incorporation of [3H]-putrescine indicated the presence of reactive glutaminyl residues in VN. When VN was incubated with TG or Factor XIIIa, in the absence of putrescine, multimeric covalent complexes were identified,
D C, Sane +5 more
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Effects of antiflammins on transglutaminase and phospholipase A2 activation by transglutaminase
International Immunopharmacology, 2006Two anti-inflammatory peptides, named antiflammins (AFs), corresponding to a region with high amino acid similarity between lipocortin-1 and uteroglobin were tested for their ability to inhibit transglutaminase (TG) and low-molecular-mass phospholipase A2 (PLA2).
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Transglutaminase-Mediated Conjugations
2019Microbial transglutaminase (MTGase) catalyzes site-specific transpeptidation between a primary amine within linkers and the side chain of glutamine 295 within deglycosylated chimeric, humanized, and human IgG1s, affording homogeneous antibody-drug conjugates (ADCs).
Yasuaki, Anami, Kyoji, Tsuchikama
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“Tissue” transglutaminase and apoptosis
1998In this paper we discuss the role of "tissue" transglutaminase (tTG) in apoptosis. This enzyme by catalizing the Ca(2+)-dependent cross-linking of intracellular proteins leads to the formation of the SDS-insoluble protein scaffold in cells undergoing programmed cell death.
F, Autuori +4 more
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2005
Preface Mammalian Transglutaminases: A Family Portrait: Mehta, K. Structure-Function Relationships of Transglutaminases - A Contemporary View: Nemes, Z.: Csosz, E. Petrovskl, G. Fesus, L. Transglutaminases and Their Substrates: Facchlano, F. Facchiano, A. Type 2 Transglutaminase and Cell Death: Placentinl, M. Amendola, A. Ciccosanti, F.
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Preface Mammalian Transglutaminases: A Family Portrait: Mehta, K. Structure-Function Relationships of Transglutaminases - A Contemporary View: Nemes, Z.: Csosz, E. Petrovskl, G. Fesus, L. Transglutaminases and Their Substrates: Facchlano, F. Facchiano, A. Type 2 Transglutaminase and Cell Death: Placentinl, M. Amendola, A. Ciccosanti, F.
openaire +1 more source