Results 211 to 220 of about 1,867,403 (306)

Transport to Hospital Without Sustained Return of Spontaneous Circulation After Out-of-Hospital Cardiac Arrest: Outcomes From Western Australia. [PDF]

Emerg Med Australas
Majewski D, Belcher J, Ball S, Finn J.
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Pediatric Increased Risk and Nonlinear Age-Dependent Risk of Hypoparathyroidism After Total Thyroidectomy: A 1914-Patient Cohort Study. [PDF]

World J Surg
Maggiore R, Licata L, Barbieri D, Ostinelli F, Vigone MC, Vincenzi G, Pitea M, Perticone F, Ciuni R, Giustina A, Rosati R.   +10 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

ECG challenge: a narrow clue in a wide QRS tachycardia. [PDF]

Eur Heart J Case Rep
Nogami A, Usui R, Uno K.
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Transient Ischemic Attack Progressing to Top-of-the-Basilar Syndrome: A Case Report. [PDF]

Am J Case Rep
Zhou G, Xu Y.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Chronic but not Transient Anemia Is Associated With Atrial Fibrillation Recurrence After Catheter Ablation. [PDF]

J Arrhythm
Kasch MG, Snæbjörnsson NT, Riis-Vestergaard LD, Rached R, Christensen DM, Binding C, Elmegaard M, Hashiba M, Nielsen SK, Lambert M, Torp-Pedersen C, Schou M, Gislason G, Mohamed AA.   +13 more
europepmc   +1 more source