Results 61 to 70 of about 215,728 (296)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
On Suicidal punishment among "Acromyrmex Versicolor" Cofoundresses: the Disadvantage in Personal Advantage [PDF]
, 2004 Publicad
Cabrales, Antonio +2 more
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Open Geosciences, 2019 A comprehensive transient electromagnetic interpretation method based on seismic wave impedance inversion has been proposed according to the advantages of seismic and transient electromagnetic exploration methods to mitigate of hidden water inrush ...
Yaoning Liu +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Stepped annealing chaotic neural network model for the channel assignment problem
Tongxin xuebao, 2008 Based on the stepped annealing method used in transient chaotic neural network,a chaotic neural network model had been improved. The dividing point in the new model was chosen according to the change of the corresponding Lyapunov exponent,and made sure ...
ZHU Xiao-jin +3 more
doaj +2 more sources
Plant Methods, 2005 Background We describe novel plasmid vectors for transient gene expression using Agrobacterium, infiltrated into Nicotiana benthamiana leaves. We have generated a series of pGreenII cloning vectors that are ideally suited to transient gene expression, by
Templeton Matthew D +8 more
doaj +1 more source
Japanese banking in the United States: From transient advantage to strategic failure
, 1993 Japanese banks instantly became major players in world financial markets when the 1985 Plaza Accord doubled the value of the yen. Access to cheap capital and long-term relationships with Japanese firms doing business abroad allowed them to undercut overseas rivals and achieve early success.
Beechler, Schon, Scher, Mark J.
openaire +2 more sources
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Jixie chuandong, 2012 The principle and re-sampling method of order tracking analysis are discussed.Then two analysis methods,steady state method and transient method are used to identify the main noise sources of the gearbox.By comparing the results,it shows that order ...
崔砚宏, 叶文龙, 黄林
doaj