Results 121 to 130 of about 1,104,045 (310)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Measurement and modelling of the transient thermal-mechanical strain field during GMA welding [PDF]

open access: yes, 2011
The state of residual stress in welded joints is a well-studied topic, and many methodsof residual stress measurement are now available. However, far less is known aboutthe transient strains which occur during the welding process, even though these ...
Colegrove, Paul A.   +3 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Leak detection using instantaneous frequency analysis [PDF]

open access: yes, 2012
Leaking pipes are a primary concern for water utilities around the globe as they compose a major portion of losses. Contemporary interest surrounding leaks is well documented and there is a proliferation of leak detection techniques. Although the reasons
M. F., Ghazali, ghazali, mohd fairusham
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Transient simulation of complex electronic circuits and systems operating at ultra high frequencies [PDF]

open access: yes, 2005
The electronics industry worldwide faces increasingly difficult challenges in a bid to produce ultra-fast, reliable and inexpensive electronic devices. Electronic manufacturers rely on the Electronic Design Automation (EDA) industry to produce consistent
Dautbegovic, Emira
core  

Code Development for System Design and Analysis of Megawatt-level Space Nuclear Power System

open access: yesYuanzineng kexue jishu
The space nuclear power system, which integrates a gas-cooled reactor with a closed Brayton cycle, is a leading candidate for megawatt-level aerospace power system due to its high efficiency, substantial power output, and independence from sunlight ...
JIANG Baihui, JI Yu, SUN Jun, SHI Lei
doaj   +1 more source

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