Results 81 to 90 of about 998,688 (259)

CalTrack: High-Throughput Automated Calcium Transient Analysis in Cardiomyocytes. [PDF]

open access: yesCirc Res, 2021
Psaras Y   +15 more
europepmc   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Code Development for System Design and Analysis of Megawatt-level Space Nuclear Power System

open access: yesYuanzineng kexue jishu
The space nuclear power system, which integrates a gas-cooled reactor with a closed Brayton cycle, is a leading candidate for megawatt-level aerospace power system due to its high efficiency, substantial power output, and independence from sunlight ...
JIANG Baihui, JI Yu, SUN Jun, SHI Lei
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Development and Verification of a Transient Analysis Tool for Solar Power Tower System with sCO2 Brayton Cycle

open access: yesEnergies
Supercritical carbon dioxide (sCO2) Brayton cycle is a promising technology for concentrating solar power systems. However, existing studies predominantly rely on steady-state or quasi-steady-state assumptions, thereby neglecting transient ...
Chenxu Xu   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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