Results 71 to 80 of about 1,104,045 (310)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

paulocaldas/Transient-Confinement-Analysis: initial release

open access: yes, 2022
first release the code is pretty much there - it just needs a little ...
Paulo Caldas, pradler
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Spreadsheet Illustration of the Transient Stability Analysis of Power Systems [PDF]

open access: yes, 2010
This paper presents a simple, yet powerful approach to introducing the topic of transient stability in a power system course. The problem of transient stability is of fundamental importance in the analysis and design of power systems.
Sastry P Kuruganty, Mark A Lau
core  

Methodology for Analysis of Electric Distribution Network Criticality Due to Direct Lightning Discharges

open access: yesEnergies, 2020
Direct lightning discharges in overhead distribution networks invariably cause serious insulation damage, frequently leading to the electric system’s partial or total shutdown. Installing lightning arresters can be very effective, and it is commonly used
Raphael Pablo de Souza Barradas   +5 more
doaj   +1 more source

Insight into Damping Sources in Turbines

open access: yesFatigue of Aircraft Structures, 2023
Blade vibrations in aircraft engines are a significant challenge that must be overcome during the design and development of modern turbine engines.
Moneta Grzegorz
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Numerical analysis of transient processes : Fundamental results of the theory, methods, and problems

open access: yes, 2007
In this chapter, we describe the state of the art in the development of general approaches and algorithms that serve as bases for solving fundamental and applied problems in the theory of transient electromagnetic fields.
Sirenko, Y. K.   +2 more
core   +1 more source

Assessment of RELAP5 model for the University of Massachusetts Lowell Research Reactor [PDF]

open access: yesNuclear Technology and Radiation Protection, 2006
RELAP5 is a system code developed at the Idaho National Environmental and Engineering Laboratory for thermal hydraulic analysis of nuclear reactors. The code RELAP5 is widely used for safety analysis studies of commercial nuclear power plants.
Bousbia-Salah Anis   +5 more
doaj   +1 more source

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