Results 101 to 110 of about 9,055 (284)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Ride Analysis For Suspension System of off-Road Tracked Vehicles [PDF]
, 1991 In this work. an attempt has been made to develop a programming package for ride analysis of off-road vehicles based upon a finite-element formulation of vehicle suspension systems.
Kasim, Salim Y.
core
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Hydraulic Transient Computer Model for San Diego Water Authority
, 2011 San Diego County Water Authority is a water wholesaler providing a safe and reliable water supply to its 24 member agencies in the San Diego region. The Water Authority supplies up to 90% of San Diego County's water, which serves more than 3 million ...
Ingeduld, Petr, Stewart, Ed, Yang, Nona
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Massive Network Failure Recovery Mechanism Based on Linear Programming
, 2016 In a scenario of recovery from massive failures,a network is repaired through multiple restoration stages because availability of repair resources is limited.During repair transition,it is crucial to ensure the accessibility of important flow for network
LIU Ke
core +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
CONFIGURATIONAL FORCES IN STRUCTURAL AND CONTINUUM OPTIMISATION [PDF]
, 2008 This thesis deals with optimisation using the principles of continuum mechanics. Both shape and mesh optimisation will be covered. A unified approach will be introduced to obtain shape and mesh optimisation for hyperelastic, hyperelastodynamic and ...
Uthman, Zana, UTHMAN, Z
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