Results 91 to 100 of about 297,414 (264)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Electromagnetic field compensation to attenuate energy leakage in TM020 mode damped cavity

Nuclear Engineering and Technology
This paper discusses the TM020 mode Higher-order Mode (HOM) damped cavity, which has a higher quality factor and lower characteristic impedance than the conventional TM010 mode. The unique electromagnetic field (EMF) distribution of the TM020 mode allows
Zhongquan Li, Kuangkuang Ye, Lei Yang, Yao Zhang, Xirui Zhou, Xue Yang, Xuerui Hao   +6 more
doaj   +1 more source

Non-Intrusive Demand Monitoring and Load Identification for Energy Management Systems Based on Transient Feature Analyses

Energies, 2012
Energy management systems strive to use energy resources efficiently, save energy, and reduce carbon output. This study proposes transient feature analyses of the transient response time and transient energy on the power signatures of non-intrusive ...
Hsueh-Hsien Chang
doaj   +1 more source

Transient receptor potential channels and energy homeostasis

Trends in Endocrinology & Metabolism, 2013
Transient receptor potential (TRP) channels are members of an ancient class of ion channels that are present in most mammalian tissues. Consistent with their wide tissue distribution, TRPs are capable of influencing diverse physiological processes including adipocyte function, energy intake and energy expenditure. TRPs function as transduction channels
openaire   +3 more sources

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Response characteristics and particle contributions of epoxy resin composite embedded with Al particles under different loading modes

Journal of Materials Research and Technology
Particle reinforced epoxy resin composites are widely used in aerospace, military defense, electronics industry and other fields because their mechanical strength, electromagnetic shielding effect and thermal stability can be controlled by adding ...
Zhenhui He, Enling Tang, Wenjin Yao, Ruizhi Wang   +3 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Propagation characteristics of H2–air detonations in double-bend ducts

Frontiers in Mechanical Engineering
Detonation transmission through compact piping and transition cavities is frequently limited by diffraction-induced shock–flame decoupling, which can lead to either recovery or complete failure depending on the available confinement and reflection ...
Yuhan Wang, Chun Zheng, Huanhao Zhang, Zhihua Chen   +3 more
doaj   +1 more source