Results 71 to 80 of about 1,037,140 (298)

Transient Accelerated Expansion and Double Quintessence

, 2004
We consider Double Quintessence models for which the Dark Energy sector consists of two coupled scalar fields. We study in particular the possibility to have a transient acceleration in these models. In both Double Quintessence models studied here, it is
David Blais, David Polarski, E. Halyo, J. L. Tonry, J. M. Cline, L. Järv, R. Kallosh, S. Hellerman, U. Alam, U. Franca, W. Fischler   +10 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Optimal design and experimental validation of 3D C/SiC-TC4 hybrid lattice structures with lightweight, thermal insulation, and excellent mechanical properties

Results in Engineering
With the development of aerospace spacecrafts (hypersonic vehicle), the strong airflow and ultra-high temperature environment encountered during service are more complex.
Mengzhou Chang, Wenbin Ma, Feigao Fan, Lulu Li, Kai Guo, Enling Tang   +5 more
doaj   +1 more source

A method for predicting IGBT junction temperature under transient condition [PDF]

, 2008
In this paper, a method to predict junction temperature of the solid-state switch under transient condition is presented. The method is based on the thermal model of the switch and instantaneous measurement of the energy loss in the device.
Ahmed, M. M. R., HASH(0x5651c9df3be8), Putrus, G. A.   +2 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Macro Meso Response and Stress Wave Propagation Characteristics of MCT High-Voltage Switch Under Shock load

Defence Technology
In order to study the dynamic and electrical coupling response characteristics of Metal Oxide Semiconductor Controlled Thyristor (MCT) high-voltage switch under the synergic action of mechanical load and high voltage, the separated Hopkinson pressure bar
Yuyang Guo, Chuang Chen, Ruizhi Wang, Enling Tang   +3 more
doaj   +1 more source

Thermoeconomic approach for the analysis of control system of energy plants [PDF]

, 2012
In this paper a thermoeconomic approach is applied to the dynamic model of a Power System in order to investigate the effects of the control system on the primary energy consumption and on the economic costs of the product.
Baccino, Bejan, El-Sayed, Giorgia Baccino, Hin, Larson, Lozano, Lozano, Rancruel, Reini, Shinskey, Verda, Verda, Vittorio Verda, Wang   +14 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Numerical simulation of cavitation and ballistic characteristics of underwater electromagnetically launching projectiles in the shear crossflow [PDF]

AIP Advances
The electromagnetic launch during underwater navigation is affected by the flow field around ships, and the crossflow velocity presents a boundary-layer distribution under the shear effect of the ship walls.
Ziyi Liu, Yunxia Xu, Xin Zhang, Wenbin Feng, Qianye Ren, Xinyue Cao, Sinuo Chen, Qi Dai   +7 more
doaj   +1 more source