Results 161 to 170 of about 854,868 (315)
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Supporting transient stability in future highly distributed power systems
, 2010 Incorporating a substantial volume of microgeneration (consumer-led rather than centrally planed) within a system that is not designed for such a paradigm could lead to conflicts in the operating strategies of the new and existing centralised generation ...
Burt, Graeme +2 more
core
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Zero overshoot and fast transient response using a fuzzy logic controller
, 2011 In some industrial process control systems it is desirable not to allow an overshoot beyond the setpoint or a threshold, this could be a safety constraint or the requirement of the system.
Mehrdadi, Bruce +2 more
core
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Research of Voltage-controlled Constant Current Source Used in DCU Simulation Test
机车电传动, 2015 According to the application requirements of DCU simulation test, a kind of voltage-controlled constant current source circuit which was based on operation amplifier was studied, and the feasibility of scheme was elaborated from the aspects of ...
LIU Weiliang +3 more
doaj
Transient CFS Response over a Multilayer Earth
, 1998 Transient electromagnetic sounding is successfully applied in mineral and groundwater exploration. Major advantage of the transient sounding is to overcome the effects of conductive overburden where frequency-domain CFS frequently fails.
Patra, H.P., Nimmagadda, Shastri
core
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source