Results 121 to 130 of about 835,487 (342)

Tank 12 data dump OME integrated thrust chamber test report, phase 1 [PDF]

The test program conducted to characterize the steady state stability, thermal, and performance characteristics of the integrated thrust chamber assembly, as well as limited tests to investigate transient characteristics are ...
Pauckert, R. P., Tobin, R. D.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Power System Transient Stability Preventive Control via Aptenodytes Forsteri Optimization with an Improved Transient Stability Assessment Model

Energies
Transient stability preventive control (TSPC), a method to efficiently withstand the severe contingencies in a power system, is mathematically a transient stability constrained optimal power flow (TSC-OPF) issue, attempting to maintain the economical and
Zhijun Xie, Dongxia Zhang, Wei Hu, Xiaoqing Han   +3 more
doaj   +1 more source

Stability of numerical integration techniques for transient rotor dynamics [PDF]

A finite element model of a rotor bearing system was analyzed to determine the stability limits of the forward, backward, and centered Euler; Runge-Kutta; Milne; and Adams numerical integration techniques.
Kascak, A. F.
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Transient Stability Assessment of Cascade Tripping of Renewable Sources Using SOS [PDF]

, 2018
Chetan Mishra, James S. Thorp, Virgilio Centeno, Anamitra Pal   +3 more
openalex   +1 more source

A NASTRAN DMAP alter for linear buckling analysis under dynamic loading [PDF]

A unique modification to the NASTRAN solution sequence for transient analysis with direct time integration (COSMIC NASTRAN rigid format 9) was developed and incorporated into a DMAP alter.
Aiello, Robert A., Grady, Joseph E.
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Study on Transient Stability of Circulation Economy Power System with High Penetration of Wind Power

, 2014
Jianping Liu, Chun Liu, Ting Rui Lu, Hai Yan Tang, Xin Tian, Zhen Wang   +5 more
openalex   +1 more source