Results 41 to 50 of about 51,905 (293)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Synchronization Dynamics in Non-Normal Networks: The Trade-Off for Optimality
Entropy, 2020 Synchronization is an important behavior that characterizes many natural and human made systems that are composed by several interacting units. It can be found in a broad spectrum of applications, ranging from neuroscience to power-grids, to mention a ...
Riccardo Muolo +3 more
doaj +1 more source
Self-Organized Synchronization and Voltage Stability in Networks of Synchronous Machines
, 2013 The integration of renewable energy sources in the course of the energy transition is accompanied by grid decentralization and fluctuating power feed-in characteristics. This raises new challenges for power system stability and design.
Friedrich, Rudolf +3 more
core +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Hierarchy and Polysynchrony in an adaptive network
, 2014 We describe a simple adaptive network of coupled chaotic maps. The network reaches a stationary state (frozen topology) for all values of the coupling parameter, although the dynamics of the maps at the nodes of the network can be non-trivial.
Botella-Soler, V., Glendinning, P.
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
IEEE Open Journal of Power Electronics, 2022 This paper addresses the transient stability of grid-forming (GFM) inverters when transitioning from the islanded to grid-connected mode. It is revealed that the reconnection of the GFM inverters to the main grid can be equivalent to a step change of the
Teng Liu +4 more
doaj +1 more source
Maximum Performance at Minimum Cost in Network Synchronization
, 2006 We consider two optimization problems on synchronization of oscillator networks: maximization of synchronizability and minimization of synchronization cost.
Adilson E. Motter +52 more
core +1 more source
Analysis and elimination of hysteresis and noisy precursors in power amplifiers [PDF]
, 2006 Power amplifiers (PAs) often exhibit instabilities leading to frequency division by two or oscillations at incommensurate frequencies. This undesired behavior can be detected through a large-signal stability analysis of the solution.
Jeon, Sanggeun +2 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source