Results 71 to 80 of about 199,554 (295)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Transient voltage stability of power systems with virtual synchronous generators or grid-following converters: analysis and enhanced control

International Journal of Electrical Power & Energy Systems
With the global energy transition, power systems are replacing synchronous generators (SGs) with voltage source converters (VSCs), which has significant implications for transient voltage stability.
Zhiying Chen, Lin Guan
doaj   +1 more source

Comparative Study of SVC and STATCOM Reactive Power Compensation for Prosumer Microgrids With DFIG-Based Wind Farm Integration

IEEE Access, 2020
Uncertainties of renewable energy sources like wind power are one of the considerable challenges of prosumer microgrids. To meet the grid codes requirements regarding the voltage stability of wind farm integration, finding the balance between providing ...
Jun Qi, Wenbin Zhao, Xiaoyan Bian
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Topologically Protected Loop Flows in High Voltage AC Power Grids

, 2016
Geographical features such as mountain ranges or big lakes and inland seas often result in large closed loops in high voltage AC power grids. Sizable circulating power flows have been recorded around such loops, which take up transmission line capacity ...
Adagideli, I., Coletta, T., Delabays, R., Jacquod, Ph.   +3 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transient stability analysis and enhancement of wind farm integrated VSC-HVDC system

CSEE Journal of Power and Energy Systems
Following severe faults in wind farm integrated voltage source converter (VSC) based high-voltage direct current (HVDC) system, wind turbines (WTs) may lose synchronization with wind farm side VSC (WFVSC), which jeopardizes the reliable delivery and ...
Guanqun Li, Hua Ye, Junru Chen, Qianying Mou   +3 more
doaj   +1 more source

Self-Organized Synchronization and Voltage Stability in Networks of Synchronous Machines

, 2013
The integration of renewable energy sources in the course of the energy transition is accompanied by grid decentralization and fluctuating power feed-in characteristics. This raises new challenges for power system stability and design.
Friedrich, Rudolf, Kamps, Oliver, Peinke, Joachim, Schmietendorf, Katrin   +3 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source