Results 81 to 90 of about 451,642 (327)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
With the global energy transition, power systems are replacing synchronous generators (SGs) with voltage source converters (VSCs), which has significant implications for transient voltage stability.
Zhiying Chen, Lin Guan
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The increasing penetration of PhotoVoltaic (PV) generation has a significant impact on the transient stability of power systems. Power electronics interface, control strategies and lack of inherent rotational element are the main factors that distinguish
Indla Rajitha Sai Priyamvada +1 more
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Multi-terminal High Voltage Direct Current (MTDC) with modular multilevel converter (MMC) is a promising technology, because it integrates diverse energy resources.
Xichang Wen +3 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Transient stability analysis and enhancement of wind farm integrated VSC-HVDC system
Following severe faults in wind farm integrated voltage source converter (VSC) based high-voltage direct current (HVDC) system, wind turbines (WTs) may lose synchronization with wind farm side VSC (WFVSC), which jeopardizes the reliable delivery and ...
Guanqun Li +3 more
doaj +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Uncertainties of renewable energy sources like wind power are one of the considerable challenges of prosumer microgrids. To meet the grid codes requirements regarding the voltage stability of wind farm integration, finding the balance between providing ...
Jun Qi, Wenbin Zhao, Xiaoyan Bian
doaj +1 more source

