Results 101 to 110 of about 451,642 (327)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Transient Synchronization Stability Control Strategy for Virtual Synchronous Converter Based on Phase Difference Locking

Technologies
With the increasing penetration of renewable energy sources, power systems require more grid-forming converters. Grid-forming converters with virtual synchronous generator control have transient stability problems similar to those of synchronous machines.
Jie Zhang, Si Yang, Kesheng Wang, Zhihao Wang, Weiyu Bao, Yunhai Lü, Hao Ding   +6 more
doaj   +1 more source

Synchrophasor based auxiliary controller to enhance power system transient voltage stability in a high penetration renewable energy scenario

2014 IEEE Symposium on Power Electronics and Machines for Wind and Water Applications, 2014
An auxiliary coordinated control approach focusing on transient voltage stability is proposed in this paper. The concept is based on support vector machine (SVM) classifier and multiple-input and multiple-output (MIMO) model predictive control (MPC) on ...
Huaiguang Jiang, Y. Zhang, J. Zhang, E. Muljadi, D. Gao   +4 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Transient voltage stability assessment based on zoned and classified dynamic reactive power reserve in power systems

Zhejiang dianli
Transient voltage stability has become a critical challenge in power systems with high penetration of renewable energy sources （RES）. Assessing transient voltage stability from a reactive power perspective provides insights into the system’s reactive ...
LI Chong, ZHAO Jinquan, DANG Jie, CUI Ting, CHEN Daojun   +4 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Stability assessment of inverter-dominated power systems considering coupling between phase angle and voltage dynamics

iEnergy
The integration of renewable energy sources (RESs) with inverter interfaces has fundamentally reshaped power system dynamics, challenging traditional stability analysis frameworks designed for synchronous generator-dominated grids.
Cong Fu, Shuiping Zhang, Shun Li, Feng Liu   +3 more
doaj   +1 more source

NETMAT: A knowledge-based grid system analysis tool [PDF]

, 1998
The increasing expansion of electric power systems renders the power system operator's task increasingly complex. The integration into energy management systems of further analytical algorithms implies that more data has to be analysed by the control ...
Irving, MR, Zitouni, S
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