Results 121 to 130 of about 451,642 (327)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Voltage Stability Mechanism of Grid-Connected Permanent Magnet Synchronous Generator Under Large Grid-Side Disturbances

Energies
As a mainstream new energy generation technology, elucidating the grid-connected voltage stability mechanisms of permanent magnet synchronous generator (PMSG) is critical for ensuring stable integration of high-penetration renewable energy.
Xun Mao, Wangchao Dong, Kai Lyv, Wei Tang, Zhen Wang, Li Guo, Yong Zhan, Yang Pu   +7 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Transient Damping of Virtual Synchronous Generator for Enhancing Synchronization Stability During Voltage Dips

CES Transactions on Electrical Machines and Systems
Virtual synchronous generators (VSGs) are widely introduced to the renewable power generation, the variable-speed pumped storage units, and so on, as a promising grid-forming solution.
Shitao Sun, Yu Lei, Guowen Hao, Yi Lu, Jindong Liu, Zhaoxin Song, Jie Zhang   +6 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Transient stability improvement of a transmission system through the application of an artificial neural network-based high-voltage direct current system

Energy Exploration & Exploitation
The increasing disturbances in power system networks present significant challenges to electrical power engineers, often leading to a loss of synchronism in grid-tied generators.
Chibuike Peter Ohanu, Uche C Ogbuefi, Emenike Ejiogu   +2 more
doaj   +1 more source

Transient Voltage Stability Assessment Method Based on CWT-ResNet

Energies
Accurate and rapid transient voltage stability assessment is crucial for the safe and stable operation of new energy bases in desert and grassland regions.
Chong Shao, Yongsheng Jin, Bolin Zhang, Xin He, Chen Zhou, Haiying Dong   +5 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Revisión sobre métodos matemáticos para el estudio de la estabilidad del voltaje en los sistemas eléctricos de potencia

Revista Científica de Ingeniería Energética, 2010
In Cuba, from the seventies of the past century, different algorithms to study stationary and transientregimes of the Cuban Electric System were developed. Those algorithms and computer programs werefocused in the study of transient stability. Currently,
Zaid García ; et al.
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source