Results 111 to 120 of about 275,457 (299)
SensorsThe use of fast transients for fault detection in long transmission networks makes the generation of controlled transients crucial. In order to maximise the information that can be extracted from the measured pressure time history (pressure signal), the ...
Francesco Castellani +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Frontiers in Astronomy and Space SciencesIn 1961, Dungey suggested that magnetic reconnection occurs due to the solar-terrestrial interaction. The interplanetary magnetic field (IMF) is thought to merge with Earth’s geomagnetic field (GMF).
G. J. Fasel +10 more
doaj +1 more source
Transient fault behavior in a microprocessor: A case study [PDF]
An experimental analysis is described which studies the susceptibility of a microprocessor based jet engine controller to upsets caused by current and voltage transients.
Duba, Patrick
core +1 more source
BMJ, 1998 “Deadly Secrets”, a QED documentary on 5 August examines the issue of neonaticide. Gwen Adshead says there is still some way to go in understanding the motivations behind this human tragedy. In 1902 Dr John Baker, a physician superintendent of Broadmoor Hospital, had this to say about women who kill their newborn children: “This class of crime ...
openaire +3 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Ergo an Open Access Journal of PhilosophyWe spend much of our adult lives thinking and reminiscing about particular events of the past, which, by their very nature, can never be repeated. What is involved in a capacity to think thoughts of this kind? In this paper, I propose that such thoughts are essentially connected with a capacity to communicate about past events, and specifically in the ...
openaire +3 more sources