Results 181 to 190 of about 275,457 (299)

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Uncovering NMDA receptor-mediated high firing activity in excitatory human neurons. [PDF]

iScience
Gameiro-Ros I, Tengolics AJ, Prytkova I, Kamarajan C, Pang ZP, Goate AM, Hart RP, Slesinger PA.   +7 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Susceptibility to Pitting Corrosion of AerMet 100 and 4340 Alloys for Aeronautical Applications. [PDF]

Materials (Basel)
Huerta-Zavala MS, Gaona-Tiburcio C, Nieves-Mendoza D, Jaquez-Muñoz JM, Cabral-Miramontes J, Maldonado-Bandala E, Croche-Belin R, Baltazar-Zamora MA, Landa-Ruiz L, Lopez-Leon LD, Olguin-Coca J, Almeraya-Calderon F.   +11 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Dendritic Inhibition Terminates Plateau Potentials in CA1 Pyramidal Neurons. [PDF]

J Neurosci
Vaasjo LO, Kotermanski SE, Patel T, Shi HJ, Machold R, Chamberland S.   +5 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

A piperidinyl amide compound enhances Ca²⁺ signaling in cardiomyocytes by increasing activity of Ca²⁺ pump. [PDF]

Biophys Rep (N Y)
Bovo E, Nikolaienko R, Yuen SL, Makarewich CA, Brinkmann M, Thomas DD, Rebbeck RT, Zima AV.   +7 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Correction for Lee et al., Saccade-related LFP power transients in the primate amygdala and hippocampus linked to the perception of social status. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source