Results 31 to 40 of about 8,761 (286)

A narrative synthesis of the impact of primary health care delivery models for refugees in resettlement countries on access, quality and coordination [PDF]

, 2013
Introduction. Refugees have many complex health care needs which should be addressed by the primary health care services, both on their arrival in resettlement countries and in their transition to long-term care. The aim of this narrative synthesis is to
Alston, Margaret, Chan, Bibiana, Cheng, I-Hao, Harris, Mark F., Joshi, Chandni, Kay, Margaret, Lo, Winston, Pottie, Kevin, Russell, Grant, Smith, Mitchell, Vasi, Shiva, Wahidi, Sayed Shukrullah   +11 more
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Time from arrival in Chile to tuberculosis diagnosis in migrants treated at primary care centers in two Metropolitan Region municipalities, Chile

Medwave
Introduction In Chile, the number of migrants affected by tuberculosis has experienced a significant increase from 7.1% in 2014 to 29.7% in 2023, ranking as the first group at risk. The objective was to estimate the time to diagnosis of tuberculosis from
Alejandra Puga-Arriagada, Jhonatan Castro Horna, Marinella Mazzei Pimentel, Gabriel Cavada Chacón, Guillermo Sequera, Javiera Varela-Torres, Olivia Horna-Campos   +6 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Crescimento urbano e doença: a esquistossomose no município de São Paulo (Brasil) Urban growth and disease: schistosomiasis in the municipality of S. Paulo (Brazil)

Revista de Saúde Pública, 1985
Procurou-se mostrar o papel da evolução urbana da cidade de São Paulo (Brasil), no surgimento das condições propícias para o estabelecimento da transmissão da esquistossomose que no Sudeste brasileiro é usualmente considerada como conseqüência do ...
Luiz Jacintho da Silva
doaj   +1 more source

The collapse of ecosystem engineer populations

, 2017
Humans are the ultimate ecosystem engineers who have profoundly transformed the world's landscapes in order to enhance their survival. Somewhat paradoxically, however, sometimes the unforeseen effect of this ecosystem engineering is the very collapse of ...
Fontanari, José F.
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Pain as a Symptom of Mental Health Conditions Among Undocumented Migrants in France: Results From a Cross-Sectional Study

International Journal of Public Health
ObjectivesThis study aimed to explore the associations between mental health status and experienced pain among undocumented migrants (UMs) in France.MethodsWe used data from the multicentric cross-sectional “Premier Pas” study conducted in the Parisian ...
Sohela Moussaoui, Sohela Moussaoui, Sohela Moussaoui, Nicolas Vignier, Nicolas Vignier, Nicolas Vignier, Stephanie Guillaume, Florence Jusot, Florence Jusot, Antoine Marsaudon, Jérôme Wittwer, Jérôme Wittwer, Paul Dourgnon   +12 more
doaj   +1 more source

Agency and the Making ofTransient Urban Spaces: Examples ofMigrants in the Cityin the Pearl River Delta, China, and Dhaka, Bangladesh

Population, Space and Place, 2014
AbstractInternal migration within Asian countries and international migration to, within, and out of Asia have been on the rise throughout the past decades. As types and pathways of migration, migrants' sociocultural and socioeconomic backgrounds, and their transnational and translocal trajectories become increasingly diverse, a majority of them move ...
Bork-Hüffer, Tabea, Etzold, Benjamin, Gransow, Bettina, Tomba, Luigi, Sterly, Harald, Suda, Kimiko, Kraas, Frauke, Flock, Ryanne   +7 more
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source