Results 41 to 50 of about 5,571 (240)

Racial prejudice and marginalisation of the Irish female migrants in the Irish Girl in America by Mary Anne Sadlier through the standpoint theory [PDF]

This paper focuses on The Irish Girl in America (1863) by the Irish author, Mary Anne Sadlier (1820-1903), who composed under the alias “J. Sadlier”. Her narratives are set against the cultural landscape of The Great Potato Famine (1845-1849) and depict ...
M. Alashjaai, Nouf Fahad, Haw Ching, Florence Toh, Mani, Manimanimangai, Bahar, Ida Baizura   +3 more
core   +1 more source

Use of health services among international migrant children – a systematic review

Globalization and Health, 2018
Background Migrant children have specific health needs, and may face difficulties in accessing health care, but not enough is known about their health service use.
Niina Markkula, Baltica Cabieses, Venla Lehti, Eleonora Uphoff, Sofia Astorga, Francisca Stutzin   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Life and health status of older migrants with hypertension in China: results from the 2018 China health and retirement longitudinal study

BMC Public Health
Background In China, internal migrants are a vulnerable population due to the challenges of the health and social system. With the increase of population aging, older migrants have an increasing risk of developing chronic conditions.
Ruilong Wang, Ailin Zhong, Jingyi Ye, Yuan Liu, Lili Sun, Jingsheng Chen, Guanyang Zou   +6 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Expert perspectives on tuberculosis screening procedures for migrants [PDF]

Jornal Brasileiro de Pneumologia
Objective: To evaluate the perspectives of tuberculosis experts from different countries regarding national screening procedures. Methods: This was a qualitative descriptive study. Data were collected by using electronic, anonymized surveys with experts
Marina Pinheiro, David N Moreira, Ana Aguiar, Raquel Duarte   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Predictors of migration in an HIV hyper-endemic rural South African community: evidence from a population-based cohort (2005–2017)

BMC Public Health, 2022
Globally, South Africa hosts the highest number of people living with HIV (PLHIV) and the unique legacy of internal labour migration continues to be a major driver of the regional epidemic, interrupting treatment-as-prevention efforts. The study examined
Armstrong Dzomba, Hae-Young Kim, Andrew Tomita, Alain Vandormael, Kaymarlin Govender, Frank Tanser   +5 more
doaj   +1 more source