Results 61 to 70 of about 5,368 (307)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Health Conditions of Immigrant, Refugee, and Asylum-Seeking Men During the COVID-19 Pandemic

COVID
The COVID-19 pandemic exacerbated structural, social, economic, and racial inequalities affecting immigrant, refugee, and asylum-seeking men—vulnerable populations often overlooked in men’s health research.
Sidiane Rodrigues Bacelo, Vagner Ferreira do Nascimento, Anderson Reis de Sousa, Sabrina Viegas Beloni Borchhardt, Luciano Garcia Lourenção   +4 more
doaj   +1 more source

Discriminación racial y Determinantes Sociales de la salud en niños y niñas migrantes: revisión narrativa

, 2023
Indexación: Scopus.Objetivo: Analizar la relación entre Determinantes Sociales de la Salud (DSS) y discrimi nación en niños, niñas y adolescentes migrantes a partir de la información disponible en la literatura científica.
Pedrero Castillo, Víctor, Macarena Chepo Chepo, Camila Venegas León, Chepo Chepo, Macarena, Victor Pedrero Castillo, Venegas León, Camila   +5 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Driving delivery and uptake of catch-up vaccination among adolescent and adult migrants in UK general practice: a mixed methods pilot study

BMC Medicine
Background Migrants in the UK and Europe face vulnerability to vaccine-preventable diseases (VPDs) due to missed childhood vaccines and doses and marginalisation from health systems. Ensuring migrants receive catch-up vaccinations, including MMR, Td/IPV,
Alison F. Crawshaw, Lucy P. Goldsmith, Anna Deal, Jessica Carter, Felicity Knights, Farah Seedat, Karen Lau, Sally E. Hayward, Joanna Yong, Desiree Fyle, Nathaniel Aspray, Michiyo Iwami, Yusuf Ciftci, Fatima Wurie, Azeem Majeed, Alice S. Forster, Sally Hargreaves   +16 more
doaj   +1 more source

COVID-19 mortality among international migrants in Brazil: spatio-temporal analysis, 2020-2022 [PDF]

Epidemiologia e Serviços de Saúde
Objective To describe the mortality profile and analyze the spatiotemporal distribution of COVID-19 mortality among international migrants residing in Brazil from 2020 to 2022.
João Roberto Cavalcante, Anete Trajman, Eduardo Faerstein   +2 more
doaj   +1 more source

Essays on Applied Network Theory. [PDF]

Network economics is a fast growing area of study, with a lot of potential for addressing a wide variety of socio-economic phenomena. Networks literally permeate our social and economic lives. The unemployed find jobs using the information and assistance
TETERYATNIKOVA, Mariya
core  

Islamic nurture in the West : approaches to parenting amongst second generation Pakistanis and Khojas in Peterborough [PDF]

, 2002
Literature on South Asian migration to Britain points to the continuing importance of religion to migrants, particularly to Muslims. Religious continuity depends on effective transmission of beliefs, practices and values to younger generations.
Smalley, Sarah Margaret Vivian
core