Results 61 to 70 of about 8,761 (286)

Health Conditions of Immigrant, Refugee, and Asylum-Seeking Men During the COVID-19 Pandemic

COVID
The COVID-19 pandemic exacerbated structural, social, economic, and racial inequalities affecting immigrant, refugee, and asylum-seeking men—vulnerable populations often overlooked in men’s health research.
Sidiane Rodrigues Bacelo, Vagner Ferreira do Nascimento, Anderson Reis de Sousa, Sabrina Viegas Beloni Borchhardt, Luciano Garcia Lourenção   +4 more
doaj   +1 more source

City regions and polycentricity: the East Midlands urban network [PDF]

, 2005
The aims of this paper were to clarify the meaning of the terms city region and polycentricy and to then examine evidence on urban centres in the East Midlands to see how far these terms describe the present configuration of the ...
Charles, D, Coombes, M, Raybould, S, Wymer, C   +3 more
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Driving delivery and uptake of catch-up vaccination among adolescent and adult migrants in UK general practice: a mixed methods pilot study

BMC Medicine
Background Migrants in the UK and Europe face vulnerability to vaccine-preventable diseases (VPDs) due to missed childhood vaccines and doses and marginalisation from health systems. Ensuring migrants receive catch-up vaccinations, including MMR, Td/IPV,
Alison F. Crawshaw, Lucy P. Goldsmith, Anna Deal, Jessica Carter, Felicity Knights, Farah Seedat, Karen Lau, Sally E. Hayward, Joanna Yong, Desiree Fyle, Nathaniel Aspray, Michiyo Iwami, Yusuf Ciftci, Fatima Wurie, Azeem Majeed, Alice S. Forster, Sally Hargreaves   +16 more
doaj   +1 more source

The role of tuberculosis control institutes in delivering tuberculosis information to domestic migrants in China: A multi-level analysis of a nationwide cross-sectional survey

International Journal of Infectious Diseases, 2019
Objectives: The aim of this study was to understand how tuberculosis (TB) control institutes raise awareness of TB among domestic migrants in China, specifically whether migrants have received TB information and how they received it.
Xia Zou, Lin Zhou, Huizhong Wu, Liang Chen, Fangjing Zhou, Cheng Gong, Jiali Ye, Li Ling   +7 more
doaj   +1 more source

Permanent and Temporary Internal Migrations in Spain, 1877-1936 - Determinants and Labour Market Impact [PDF]

Preliminary ...
Javier Silvestre
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

COVID-19 mortality among international migrants in Brazil: spatio-temporal analysis, 2020-2022 [PDF]

Epidemiologia e Serviços de Saúde
Objective To describe the mortality profile and analyze the spatiotemporal distribution of COVID-19 mortality among international migrants residing in Brazil from 2020 to 2022.
João Roberto Cavalcante, Anete Trajman, Eduardo Faerstein   +2 more
doaj   +1 more source