Results 81 to 90 of about 8,761 (286)

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

The role of differential delays in integrating transient visual and proprioceptive information

Frontiers in Psychology, 2014
Many actions involve limb movements towards a target. Visual and proprioceptive estimates are available online, and by optimally combining (Ernst and Banks, 2002) both modalities during the movement, the system can increase the precision of the hand ...
Brendan Daniel Cameron, Brendan Daniel Cameron, Cristina ede la Malla, Cristina ede la Malla, Joan eLópez-Moliner, Joan eLópez-Moliner   +5 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

The spread of infectious diseases in migration routes between caravans and resident communities: Modelling yellow fever in Central America

The Journal of Climate Change and Health
Introduction: Climate-sensitive diseases are significantly affected by weather patterns and the social consequences of a changing climate. In this context, epidemics and human mobility can interact, leading to unpredictable impacts on both human and ...
Sabrina Soares Simon, Marcos Amaku, Eduardo Massad   +2 more
doaj   +1 more source

Living with Change Among a Transient Population: <i>Narratives and Practices of Collective Belonging among Swedish Migrants on the Costa del Sol in Spain¹</i>

Nordic Journal of Migration Research, 2017
The article explores how the Swedish migrants narrate and practice collective belonging as strategies to handle life in a region characterised by a transient and circulating population on the Costa del Sol, Spain. It is based on an ethnographic research within the Swedish infrastructure of organizations, institutions, and private enterprises, in ...
openaire   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

L'approche transculturelle du soin au bénéfice des patients migrants atteints d'état de stress post-traumatique: travail de Bachelor [PDF]

, 2017
Chez les patients migrants, un certain nombre de barrières existent. Elles sont la conséquence du changement de contexte environnemental que l’expérience migratoire implique, de la reconstruction identitaire qui en découle et des expériences traumatiques
Berthet, Guillaume, Boloré, Sylvain
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Reducing loneliness among migrant and ethnic minority people: a participatory evidence synthesis

Public Health Research, 2020
Background: To date, there has been little research into the causes of, and solutions to, loneliness among migrant and ethnic minority people. Objectives: The objectives were to synthesise available evidence and produce new insights relating to ...
Sarah Salway, Elizabeth Such, Louise Preston, Andrew Booth, Maria Zubair, Christina Victor, Raghu Raghavan   +6 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source