Results 101 to 110 of about 5,368 (307)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

A cross-sectional study on knowledge of coronavirus disease 2019 and related factors among Vietnamese/Nepalese students in Japan

Discover Social Science and Health
Aim This study aimed to assess the knowledge level of coronavirus disease 2019 and identify related factors, including information channels, among Vietnamese/Nepalese students in Japanese language schools. Methods A self-administered online questionnaire
Madoka Takemura, Michiyo Higuchi
doaj   +1 more source

Reproduction, growth and migration of fishes in a regulated lowland tributary: Potential recruitment to the River Meuse

, 2006
Many European rivers are characterized by a canalized main channel, steep stony embankments, the absence of aquatic vegetation, regulated flow dynamics, reduced hydrological connectivity to the floodplains and a lack of spawning and nursery areas for ...
Verberk, W.C.E.P., Pollux, B.A.J., Pollux, P.M.J., Velde, G., Van Der, Pollux, B.J.A., van der Velde, G., Velde, G. van der, Korosi, A., Velde van der, G.   +8 more
core   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

A systematic review of migrant women's experiences of successful exclusive breastfeeding in high‐income countries

Maternal and Child Nutrition
The World Health Organisation recommends exclusive breastfeeding for the first 6 months after childbirth. However, since breastfeeding is influenced by cultural practice, it differs between migrant mothers and nonmigrant mothers.
Chieko Izumi, Joshua Trigg, Jacqueline H. Stephens   +2 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Children’s Drawings as a Tool to Explore the Emotional Experience of Migrant Children in Dental Care: A Qualitative Study in Italy

Children
Background: In multicultural healthcare systems such as the Italian one, migrant children may experience dental care as particularly stressful because linguistic and cultural barriers can limit communication, emotional expression, and understanding of ...
Lucia Giannini, Chiara Alessandra Dini, Gregorio Menozzi, Maria Assunta Mauri, Federica Macrì, Ioana Roxana Bordea, Francesca Calò, Lucia Memè, Andrea Palermo   +8 more
doaj   +1 more source

Programme, policies, people: the interaction between Bosnian refugees and British society [PDF]

This thesis analyses the situation of refugees from Bosnia-Herzegovina that arrived in Britain as part of an organised programme. It represents a contribution towards the theoretical understanding of refugees, and develops and refines the theories of ...
Kelly, Lynnette
core