Results 91 to 100 of about 1,048,939 (345)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

The third transit of snow-line exoplanet Kepler-421b [PDF]

, 2016
The Kepler Mission has uncovered a handful of long-period transiting exoplanets that orbit from the cold outer reaches of their systems, despite their low transit probabilities.
Dalba, P. A., Muirhead, P. S.
core  

Transitions [PDF]

The Oncologist, 2021
openaire   +4 more sources

Inequitable job accessibility across educational and hukou groups in Beijing: An analysis of transit-based accessibility to sectoral jobs

Journal of Transport and Land Use, 2018
This paper documents inequitable transit-based accessibility to sectoral jobs among population groups with different educational attainment and hukou status in Beijing, China.
Tieshan Sun, Yingling Fan
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Changes in Transit Use and Service and Associated Changes in Driving Near a New Light Rail Transit Line, MTI Report 12-44 [PDF]

, 2015
Los Angeles is pursuing possibly the most ambitious rail transit investment program in the nation with plans to open six new rail transit lines between now and 2019.
Boarnet, Marlon, Houston, Doug, Nixon, Hilary, Spears, Steven   +3 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Normal colon transit time

, 2021
Mohammad Niknejad
openalex   +1 more source

Global Qibla Direction Using Stellar Transit at Kaaba Latitude

Al-Hilal
The global rashd al-qiblah is currently considered the most accurate and easily applicable method for measuring the qibla direction, as it utilizes the sun’s shadow during its transit above the Kaaba.
Fathurrahman Fathurrahman, Fika Afhamul Fuscha   +1 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source