Results 91 to 100 of about 983,653 (300)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Belarusian-Lithuanian Relations: How Politics Beats the Economy [PDF]

Современная Европа
The article analyses the dynamics of Belarusian-Lithuanian relations in the post-Soviet period. The historical, cultural and political-economic aspects of the relationship between the two countries are considered. It is noted that Lithuania is the second
Vsevolod V. Shimov
doaj   +1 more source

Performance Measures to Assess Resiliency and Efficiency of Transit Systems [PDF]

, 2017
Transit agencies are interested in assessing the short-, mid-, and long-term performance of infrastructure with the objective of enhancing resiliency and efficiency.
Bartin, Bekir, Deka, Devajyoti, El-Awar, Ayman, Lou, Peng, Morgul, Ender Faruk, Mudigonda, Sandeep, Na, Chaekuk, Nassif, Hani, Zhu, Yuan, Özbay, Kaan   +9 more
core   +1 more source

The Exoplanet Eccentricity Distribution from Kepler Planet Candidates [PDF]

, 2012
The eccentricity distribution of exoplanets is known from radial velocity surveys to be divergent from circular orbits beyond 0.1 AU. This is particularly the case for large planets where the radial velocity technique is most sensitive.
Barnes, Batalha, Borucki, Borucki, Burke, Butler, David R. Ciardi, Dawn M. Gelino, Fischer, Ford, Ford, Goldreich, Howard, Johnson, Jurić, Kane, Kane, Kane, Kaspar von Braun, Kipping, Lissauer, Lissauer, Lissauer, Lovis, Malmberg, Mandel, Matsumura, Moorhead, Plavchan, Pont, Seager, Shen, Smalley, Stephen R. Kane, Terrien, von Braun, Wang, Wright, Zakamska   +38 more
core   +4 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Changes in Transit Use and Service and Associated Changes in Driving Near a New Light Rail Transit Line, MTI Report 12-44 [PDF]

, 2015
Los Angeles is pursuing possibly the most ambitious rail transit investment program in the nation with plans to open six new rail transit lines between now and 2019.
Boarnet, Marlon, Houston, Doug, Nixon, Hilary, Spears, Steven   +3 more
core   +1 more source

$\texttt{PyTranSpot}$ - A tool for multiband light curve modeling of planetary transits and stellar spots

, 2017
Several studies have shown that stellar activity features, such as occulted and non-occulted starspots, can affect the measurement of transit parameters biasing studies of transit timing variations and transmission spectra. We present $\texttt{PyTranSpot}
Cubillos, P. E., Fossati, L., Guenther, E. W., Hanslmeier, A., Juvan, Ines G., Lammer, H., Lendl, M., Tregloan-Reed, J.   +7 more
core   +1 more source

The Spitzer search for the transits of HARPS low-mass planets - I. No transit for the super-Earth HD 40307b [PDF]

, 2010
We have used Spitzer and its IRAC camera to search for the transit of the super-Earth HD 40307b. The transiting nature of the planet could not be firmly discarded from our first photometric monitoring of a transit window because of the uncertainty coming
B.-O. Demory, Beaulieu, Bouchy, Bouchy, Butler, C. Lovis, Charbonneau, Charbonneau, Charbonneau, Charbonneau, Chib, D. Deming, D. Queloz, D. Segransan, Deming, Demory, F. Pepe, Forveille, Gardner, Gelman, Gillon, Gillon, Gillon, Gillon, Giménez, Henry, Johnson, Knutson, Knutson, Léger, M. Gillon, M. Mayor, Mandel, Massana, Mayor, Mayor, Mayor, P. Magain, Queloz, Rogers, S. Delmelle, S. Seager, S. Udry, Santos, Seager, Skrutskie, Sousa, Swain, Udry, Valencia, Vidal-Majar, Werner, Winn   +52 more
core   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source