Results 71 to 80 of about 1,048,939 (345)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An Assessment of Performance Measures in the Transportation Development Act [PDF]

open access: yes, 2019
"This report examines the performance measures requirements in California’s Transportation Development Act (TDA) of 1971. The TDA is an important source of funding for the state’s public transit agencies, representing approximately 18 percent of their ...
Gahbauer, John   +5 more
core  

Mapping a star with transits: orbit precession effects in the Kepler-13 system [PDF]

open access: yes, 2013
Kepler-13b (KOI-13.01) is a most intriguing exoplanet system due to the rapid precession rate, exhibiting several exotic phenomena. We analyzed $Kepler$ Short Cadence data up to Quarter 14, with a total time-span of 928 days, to reveal changes in transit
Kiss, L. L.   +2 more
core   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The puzzle of transit: the institutionalist answer to the disappearance of the “Second World”

open access: yesStudia Humanitatis, 2016
The article ponders upon background and outcomes of development strategies chosen by post-Socialist states within the last 25 years, the fundamental limits and opportunities of choices, and evaluation of their progress scaled between traditions and ...
Mykhaylenko Maksym Valeriyovych
doaj  

Between EU Membership and the Sanctions Regime against Russia: Factors behind the Collapse of Estonian Transit Sector [PDF]

open access: yesRomanian Journal of European Affairs, 2019
The article aims to investigate the main factors behind changes in the transit flows in Estonian transit sector. Towards this end, the current study used not only previous academic works and official statistics but also a comprehensive survey among ...
Viljar Veebel, Raul Markus
doaj  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Transit Performance Measures in California [PDF]

open access: yes, 2016
This research is the result of a California Department of Transportation (Caltrans) request to assess the most commonly available transit performance measures in California. Caltrans wanted to understand performance measures and data used by Metropolitan
Issac, Emily, Rodier, Caroline
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Can planetary instability explain the Kepler dichotomy?

open access: yes, 2012
The planet candidates discovered by the Kepler mission provide a rich sample to constrain the architectures and relative inclinations of planetary systems within approximately 0.5 AU of their host stars.
Anders Johansen   +30 more
core   +1 more source

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