Results 31 to 40 of about 15,713,710 (286)
Heliyon, 2023 The absence of comprehensive and structured planning strategies for pedestrians, especially for those with functional diversity, promotes the need to address tools that allow broadening the spectrum of their assessment and prioritizing the inclusive ...
Yaqueline Guevara-Quinchúa +1 more
doaj +1 more source
Transit Oriented Development: How to Make Cities More Compact, Connected and Coordinated: Recommendations for Brazilian Municipalities [PDF]
, 2021 The monograph “Transit Oriented Development: how to make cities more compact, connected and coordinated” derives from the work carried out by the IDB, MDR and IDOM on Transit Oriented Development (TOD) in Brazil.
Inter-American Development Bank
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Transit and Regional Economic Development
, 2011 The types of jobs locating near transit are changing, and the ones that have grown are the places where our economy is likely to continue adding jobs such as professional sectors.
Center for Transit-Oriented Development
core +2 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Town and Regional Planning, 2023 Apartheid’s impact on South Africa’s urban spatial patterns persists, resulting in spatial fragmentation and inequality. Unsustainable urban sprawl exacerbates challenges related to economic access.
Bradley van der Walt, Ockert Pretorius
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
JGEET: Journal of Geoscience, Engineering, Environment and TechnologyCrucial research into Transit Oriented Development (TOD) in the Setiabudi District of South Jakarta highlights its significance as a burgeoning business center.
Herika Muhamad Taki +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source