Results 31 to 40 of about 11,356 (264)
Town and Regional Planning, 2023 Apartheid’s impact on South Africa’s urban spatial patterns persists, resulting in spatial fragmentation and inequality. Unsustainable urban sprawl exacerbates challenges related to economic access.
Bradley van der Walt, Ockert Pretorius
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
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JGEET: Journal of Geoscience, Engineering, Environment and TechnologyCrucial research into Transit Oriented Development (TOD) in the Setiabudi District of South Jakarta highlights its significance as a burgeoning business center.
Herika Muhamad Taki +2 more
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Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
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ANALISA KELAYAKAN PENERAPAN TRANSIT ORIENTED DEVELOPMENT PADA KOTA LHOKSEUMAWE
ArsiteknoLhokseumawe termasuk dalam salah satu kota pusat pertumbuhan di Provinsi Aceh. Pertumbuhan ini ditandai dengan meningkatnya penggunaan kendaraan pribadi yang marak.
Nahrul Hayawan Dradisa
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
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Transit-Oriented Development: Learnings from Global Examples
LogiTransit-oriented development (TOD) is a method employed in area-based developments to address civic mobility, automation, inequality, community, equality, and climate change in metropolises.
Bhagwati Pushpak, Kumar Manoj
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The Social Justice Impact of the Transit-Oriented Development
Societies, 2020 Transit-oriented development (TOD) is often considered a solution for automobile dependency in the pursuit of sustainability. Although TOD has shown various benefits as sustainable development and smart growth, there are potential downsides, such as ...
Seunghoon Kim
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