Results 41 to 50 of about 502,720 (355)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Open for business? Effects of Los Angeles Metro Rail construction on adjacent businesses

Journal of Transport and Land Use, 2017
Recent court cases and news reports have focused on the effects of transit construction on business revenue and survival, yet the topic is underexplored in the scholarly literature. This paper examines whether transit construction negatively affected the
Rosalie Singerman Ray
doaj   +1 more source

Transit-oriented development, development corridors and economic access: The Louis Botha development corridor’s impact

Town and Regional Planning, 2023
Apartheid’s impact on South Africa’s urban spatial patterns persists, resulting in spatial fragmentation and inequality. Unsustainable urban sprawl exacerbates challenges related to economic access.
Bradley van der Walt, Ockert Pretorius
doaj   +1 more source

Conceptualising justice in transit-oriented development (TOD): towards an analytical framework

Transport reviews
Originally conceived to create dense, diverse and mixed-used communities that are inclusive and sustainable communities, Transit-oriented Development (“TOD”) has come under increasing academic scrutiny on its negative implications on equity and justice ...
Marquis K.F. Yip, S. Ramezani, Louise Meijering, T. Tillema, Jos Arts   +4 more
semanticscholar   +1 more source

Los Angeles’s Transit-Oriented Communites Program: Challenges and Opportunities [PDF]

, 2019
In recent years, municipalities throughout California have struggled to meet housing needs, and construction of new housing units in the state has not kept apace of demand, resulting in increased housing costs that rank among the highest in the nation ...
Stein, Julia E.
core  

Planning and Policymaking for Transit-Oriented Development, Transit, and Active Transport in California Cities [PDF]

, 2020
This report provides research findings from the first year of a two-year research project on patterns of local policymaking in California to support transit-oriented development (TOD), transit, and active transport. The project aims to assess motivations,
Barbour, Elisa, Chaudhary, Gyanendra, Grover, Salvador, Handy, Susan, Lamoureaux, Yulia   +4 more
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Analysis of Determining the Potential for Transit Oriented Development in the Setiabudi District Area, South Jakarta, Indonesia

JGEET: Journal of Geoscience, Engineering, Environment and Technology
Crucial research into Transit Oriented Development (TOD) in the Setiabudi District of South Jakarta highlights its significance as a burgeoning business center.
Herika Muhamad Taki, Bethany Jaffa Rani, Muhammad Dimas Elvin Putra   +2 more
doaj   +1 more source

Transit-Oriented Development: Towards Achieving Sustainable Transport and Urban Development in Jakarta Metropolitan, Indonesia

Sustainability, 2022
Transit-Oriented Development (TOD) is advocated for achieving sustainable transportation through development around transit stations. TOD’s global implementation revealed varied outcomes, with many cities failing to achieve the intended objectives.
H. Hasibuan, M. Mulyani
semanticscholar   +1 more source