Results 101 to 110 of about 274,344 (248)

Structural analysis of the NifL‐NifA complex reveals the molecular basis of anti‐activation of nitrogen fixation gene expression in Azotobacter vinelandii

open access: yesThe FEBS Journal, EarlyView.
Using cryo‐EM combined with biochemical and genetic approaches, we mapped the interaction surface between NifL and NifA to gain insights into the regulation of nitrogen fixation genes in A. vinelandii. Our findings suggest that NifL, a homolog of histidine kinases lacking phosphorylation activity, evolved to act as a steric block of NifA activity ...
Marcelo Bueno Batista   +6 more
wiley   +1 more source

TOI-2015 b: A Warm Neptune with Transit Timing Variations Orbiting an Active Mid-type M Dwarf

open access: yesThe Astronomical Journal
We report the discovery of a close-in ( P _orb = 3.349 days) warm Neptune with clear transit timing variations (TTVs) orbiting the nearby ( d = 47.3 pc) active M4 star, TOI-2015.
Sinclaire E. Jones   +31 more
doaj   +1 more source

The fc fragment of IgMs binds C1q to activate the first step of the classical complement pathway, while inhibiting complement‐dependent cytotoxicity

open access: yesThe FEBS Journal, EarlyView.
Multimeric IgM‐fragment crystallizable region (Fc) fragments retain the ability to bind C1q and initiate the classical complement pathway, leading to C4 activation and deposition in vitro. However, the Fc cores can also inhibit complement‐dependent cytotoxicity by competing with surface‐bound antibodies for C1q engagement.
Andrea J. Pinto   +9 more
wiley   +1 more source

The hidden science of haptics: A pedagogical review of tactile evaluation in cosmetics

open access: yesInternational Journal of Cosmetic Science, EarlyView.
This review explores the physiological basis of tactile perception and critically examines classical and emerging sensory methods used in cosmetics, advocating for broader methodological integration and recognition of sensory analysis in the field. Abstract Sensory analysis is a cornerstone of cosmetic development, yet remains underrepresented in peer ...
Morgane Postec   +2 more
wiley   +1 more source

Confirming the Warm and Dense Sub-Saturn TIC 139270665 b with the Automated Planet Finder and Unistellar Citizen Science Network

open access: yesThe Astronomical Journal
We report the discovery and confirmation of the Transiting Exoplanet Survey Satellite (TESS) single-transit, warm and dense sub-Saturn, TIC 139270665 b. This planet is unusually dense for its size: with a bulk density of 2.13 g cm ^−3 (0.645 R _J , 0.463
Daniel O’Conner Peluso   +62 more
doaj   +1 more source

Inflammatory and Myocardial Biomarker Response Following Pulmonary Vein Isolation: Cryoballoon Versus Balloon‐in‐Basket Pulsed Field Ablation

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Cryoballoon ablation (CB) is a well‐established thermal technique for pulmonary vein isolation (PVI), while balloon‐in‐basket pulsed field ablation (BiB‐PFA) represents a novel non‐thermal alternative. Both single‐shot systems may trigger systemic inflammation and myocardial injury, yet direct comparisons are lacking.
Jan‐Per Wenzel   +9 more
wiley   +1 more source

The gatekeepers of growth: The neural roles and regulation of growth hormone‐releasing hormone neurons

open access: yesJournal of Neuroendocrinology, EarlyView.
Abstract The neuroendocrine control of growth is mediated by the hypothalamic–pituitary–somatic (HPS) axis. This involves the hypothalamic release of growth hormone‐releasing hormone (GHRH), which stimulates the pituitary secretion of growth hormone (GH).
Bradley B. Jamieson
wiley   +1 more source

OrCAS: Origins, Compositions, and Atmospheres of Sub-Neptunes. I. Survey Definition

open access: yesThe Astronomical Journal
Sub-Neptunes—volatile-rich exoplanets smaller than Neptune—are intrinsically the most common type of planet known. However, the formation and nature of these objects, as well as the distinctions between subclasses (if any), remain unclear.
Ian J. M. Crossfield   +63 more
doaj   +1 more source

Determination of Reference Intervals for Selected Liver Biomarkers With Focus on Pre‐ and Postanalytical Factors in Lactating Dairy Cattle

open access: yesVeterinary Clinical Pathology, EarlyView.
ABSTRACT Background Measurement of liver enzymes and metabolites for both clinically healthy and sick cattle is a routine part of dairy herd management. Reference intervals (RIs) are influenced by many variables, including pregnancy, breeding, and geographical variables, and can shift over time.
Anna Theile   +2 more
wiley   +1 more source

Reference Intervals of Selected Serum and Plasma Biochemical Analytes in Clinically Healthy Multiparous Holstein Cows During the Periparturient Period

open access: yesVeterinary Clinical Pathology, EarlyView.
ABSTRACT Background Monitoring the metabolic changes during the periparturient period is crucial. Objective We aimed to establish reference intervals (RIs) of several serum and plasma biochemical variables in multiparous periparturient Holstein dairy cows. Methods A total of 238 multiparous dry cows from six commercial dairy farms were enrolled.
Nektarios Siachos   +6 more
wiley   +1 more source

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