Results 101 to 110 of about 13,251,368 (347)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Speed-of-light pulses in the massless nonlinear Dirac equation with a potential [PDF]

open access: yes, 2017
We consider the massless nonlinear Dirac (NLD) equation in $1+1$ dimension with scalar-scalar self-interaction $\frac{g^2}{2} (\bar{\Psi} \Psi)^2$ in the presence of three external electromagnetic potentials $V(x)$, a potential barrier, a constant ...
Bishop, A. R.   +4 more
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Analysis of spatial features and determination of metropolitan area boundaries in the Guanzhong region affected by intercity rail transit

open access: yesDiscover Applied Sciences
This study explores how intercity rail transit reshapes spatial structures, which underpins the optimization of regional resource allocation. Taking 54 county-level units in the Guanzhong region as research subjects, we constructed a dual-model ...
Chunjie Cai, Pei Zhang
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

TraMoS IV: Discarding the Quick Orbital Decay Hypothesis for OGLE-TR-113b

open access: yes, 2015
In the context of the TraMoS project we present nine new transit observations of the exoplanet OGLE-TR-113b observed with the Gemini South, Magellan Baade, Danish-1.54m and SOAR telescopes. We perform a homogeneous analysis of these new transits together
Adams, E. R.   +4 more
core   +1 more source

Shot Noise in Linear Macroscopic Resistors [PDF]

open access: yes, 2004
We report on a direct experimental evidence of shot noise in a linear macroscopic resistor. The origin of the shot noise comes from the fluctuation of the total number of charge carriers inside the resistor associated with their diffusive motion under ...
A. van der Ziel   +14 more
core   +3 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Earth's Atmospheric Electricity Parameter Response During Venus Transit

open access: yesTerrestrial, Atmospheric and Oceanic Sciences, 2015
Venus transited across the Sun on 06 June 2012, introducing significant contribution to the tidal characteristics of the solar atmosphere. _ atmosphere was perturbed due to an anomalous Coronal Mass Ejection (CME) and γ-radiationγ-radiation influenced by
Syam Sundar De   +4 more
doaj   +1 more source

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