Results 111 to 120 of about 9,228,850 (295)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Tumorigenic Potential of Transit-Amplifying Prostate Cells [PDF]
, 2010 Abstract : A better understanding of the identities of the target cells responsible for prostate cancer development and the molecular pathways in these cells are essential for the development of new diagnostic, prognostic and therapeutic approaches.
openaire +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Green Energy and Intelligent TransportationThis paper evaluates rail transit within the context of the transit policies implemented in Lima, Peru. First it reviews the implementation of rapid transit, and bus reform.
Manuel Jose Martinez
doaj +1 more source
Urban commuting dynamics in response to public transit upgrades: A big data approach.
PLoS ONE, 2019 Public transit, especially urban rail systems, plays a vital role in shaping commuting patterns. Compared with census data and survey data, large-scale and real-time big data can track the impacts of urban policy implementations at finer spatial and ...
Qi-Li Gao +6 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Journal of Advanced TransportationThis study explores transit-oriented development (TOD) in Dhaka City using optimization algorithms to provide urban planning and policy-making insights.
Md. Anwar Uddin +3 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Evaluating Transit-Oriented Development Effectiveness
, 2012 As resources become scare, transportation costs rise, and congestion gets worse, developing transit alternatives will become increasingly important. Transit-oriented development is a sustainable method for building communities that are less dependent on
Armstrong, Chelsey
core
Transit Attractiveness: Systematic Approach to Transit Performance Measurement
, 2006 Transit performance measures typically have focused on attributes of service supply, such as capacity, passenger loading, frequency, and reliability. These measures are effective in describing the quality of transit service available at a given location,
Pitstick, Mark E +2 more
core +1 more source