Results 131 to 140 of about 13,251,368 (347)

On the influence of blends on the potential of ground-based transit surveys [PDF]

open access: yes, 2007
Transit surveys have to observe many stars all at once in order to compensate for the rarity of the searched events. Such surveys, especially the ones observing a deep field of view and/or broadening their stellar images, have to deal with a relatively ...
Gillon, M., Magain, P.
core   +1 more source

Critical evaluation of transit policies in Lima, Peru; resilience of rail rapid transit (Metro) in a developing country

open access: yesGreen Energy and Intelligent Transportation
This paper evaluates rail transit within the context of the transit policies implemented in Lima, Peru. First it reviews the implementation of rapid transit, and bus reform.
Manuel Jose Martinez
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Synergistic Interactions of Dynamic Ridesharing and Battery Electric Vehicles Land Use, Transit, and Auto Pricing Policies [PDF]

open access: yes, 2015
It is widely recognized that new vehicle and fuel technology is necessary, but not sufficient, to meet deep greenhouse gas (GHG) reductions goals for both the U.S. and the state of California.
Alemi, Farzad   +2 more
core   +1 more source

Urban commuting dynamics in response to public transit upgrades: A big data approach.

open access: yesPLoS ONE, 2019
Public transit, especially urban rail systems, plays a vital role in shaping commuting patterns. Compared with census data and survey data, large-scale and real-time big data can track the impacts of urban policy implementations at finer spatial and ...
Qi-Li Gao   +6 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

The \^G Search for Extraterrestrial Civilizations with Large Energy Supplies. IV. The Signatures and Information Content of Transiting Megastructures

open access: yes, 2015
Arnold (2005), Forgan (2013), and Korpela et al. (2015) noted that planet-sized artificial structures could be discovered with Kepler as they transit their host star.
Cartier, Kimberly M. S.   +4 more
core   +1 more source

Leveraging Ant Colony and Particle Swarm Optimization Algorithms for Assessing the Transit-Oriented Development Potential: A Case Study of Dhaka, Bangladesh

open access: yesJournal of Advanced Transportation
This study explores transit-oriented development (TOD) in Dhaka City using optimization algorithms to provide urban planning and policy-making insights.
Md. Anwar Uddin   +3 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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